Disclosing Critical Voice Features for Discriminating between Depression and Insomnia—A Preliminary Study for Developing a Quantitative Method

<b>Background:</b> Depression and insomnia are highly related—insomnia is a common symptom among depression patients, and insomnia can result in depression. Although depression patients and insomnia patients should be treated with different approaches, the lack of practical biological ma...

Full description

Bibliographic Details
Main Authors: Ray F. Lin, Ting-Kai Leung, Yung-Ping Liu, Kai-Rong Hu
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Healthcare
Subjects:
Online Access:https://www.mdpi.com/2227-9032/10/5/935
_version_ 1797499421118693376
author Ray F. Lin
Ting-Kai Leung
Yung-Ping Liu
Kai-Rong Hu
author_facet Ray F. Lin
Ting-Kai Leung
Yung-Ping Liu
Kai-Rong Hu
author_sort Ray F. Lin
collection DOAJ
description <b>Background:</b> Depression and insomnia are highly related—insomnia is a common symptom among depression patients, and insomnia can result in depression. Although depression patients and insomnia patients should be treated with different approaches, the lack of practical biological markers makes it difficult to discriminate between depression and insomnia effectively. <b>Purpose:</b> This study aimed to disclose critical vocal features for discriminating between depression and insomnia. <b>Methods:</b> Four groups of patients, comprising six severe-depression patients, four moderate-depression patients, ten insomnia patients, and four patients with chronic pain disorder (CPD) participated in this preliminary study, which aimed to record their speaking voices. An open-source software, openSMILE, was applied to extract 384 voice features. Analysis of variance was used to analyze the effects of the four patient statuses on these voice features. <b>Results:</b> statistical analyses showed significant relationships between patient status and voice features. Patients with severe depression, moderate depression, insomnia, and CPD reacted differently to certain voice features. Critical voice features were reported based on these statistical relationships. <b>Conclusions:</b> This preliminary study shows the potential in developing discriminating models of depression and insomnia using voice features. Future studies should recruit an adequate number of patients to confirm these voice features and increase the number of data for developing a quantitative method.
first_indexed 2024-03-10T03:47:06Z
format Article
id doaj.art-32d6369c5dae4f0a920edd1c8b6b72e3
institution Directory Open Access Journal
issn 2227-9032
language English
last_indexed 2024-03-10T03:47:06Z
publishDate 2022-05-01
publisher MDPI AG
record_format Article
series Healthcare
spelling doaj.art-32d6369c5dae4f0a920edd1c8b6b72e32023-11-23T11:15:21ZengMDPI AGHealthcare2227-90322022-05-0110593510.3390/healthcare10050935Disclosing Critical Voice Features for Discriminating between Depression and Insomnia—A Preliminary Study for Developing a Quantitative MethodRay F. Lin0Ting-Kai Leung1Yung-Ping Liu2Kai-Rong Hu3Department of Industrial Engineering and Management, Yuan Ze University, Taoyuan 32003, TaiwanDepartment of Radiology, Taoyuan General Hospital, Ministry of Health and Welfare, No. 1492, Zhongshan Rd., Taoyuan City 33004, TaiwanDepartment of Industrial Engineering and Management, Chaoyang University of Technology, Taichung 413310, TaiwanDepartment of Industrial Engineering and Management, Yuan Ze University, Taoyuan 32003, Taiwan<b>Background:</b> Depression and insomnia are highly related—insomnia is a common symptom among depression patients, and insomnia can result in depression. Although depression patients and insomnia patients should be treated with different approaches, the lack of practical biological markers makes it difficult to discriminate between depression and insomnia effectively. <b>Purpose:</b> This study aimed to disclose critical vocal features for discriminating between depression and insomnia. <b>Methods:</b> Four groups of patients, comprising six severe-depression patients, four moderate-depression patients, ten insomnia patients, and four patients with chronic pain disorder (CPD) participated in this preliminary study, which aimed to record their speaking voices. An open-source software, openSMILE, was applied to extract 384 voice features. Analysis of variance was used to analyze the effects of the four patient statuses on these voice features. <b>Results:</b> statistical analyses showed significant relationships between patient status and voice features. Patients with severe depression, moderate depression, insomnia, and CPD reacted differently to certain voice features. Critical voice features were reported based on these statistical relationships. <b>Conclusions:</b> This preliminary study shows the potential in developing discriminating models of depression and insomnia using voice features. Future studies should recruit an adequate number of patients to confirm these voice features and increase the number of data for developing a quantitative method.https://www.mdpi.com/2227-9032/10/5/935depressioninsomniaopenSMILEvoice featurecomputer-aided diagnosis
spellingShingle Ray F. Lin
Ting-Kai Leung
Yung-Ping Liu
Kai-Rong Hu
Disclosing Critical Voice Features for Discriminating between Depression and Insomnia—A Preliminary Study for Developing a Quantitative Method
Healthcare
depression
insomnia
openSMILE
voice feature
computer-aided diagnosis
title Disclosing Critical Voice Features for Discriminating between Depression and Insomnia—A Preliminary Study for Developing a Quantitative Method
title_full Disclosing Critical Voice Features for Discriminating between Depression and Insomnia—A Preliminary Study for Developing a Quantitative Method
title_fullStr Disclosing Critical Voice Features for Discriminating between Depression and Insomnia—A Preliminary Study for Developing a Quantitative Method
title_full_unstemmed Disclosing Critical Voice Features for Discriminating between Depression and Insomnia—A Preliminary Study for Developing a Quantitative Method
title_short Disclosing Critical Voice Features for Discriminating between Depression and Insomnia—A Preliminary Study for Developing a Quantitative Method
title_sort disclosing critical voice features for discriminating between depression and insomnia a preliminary study for developing a quantitative method
topic depression
insomnia
openSMILE
voice feature
computer-aided diagnosis
url https://www.mdpi.com/2227-9032/10/5/935
work_keys_str_mv AT rayflin disclosingcriticalvoicefeaturesfordiscriminatingbetweendepressionandinsomniaapreliminarystudyfordevelopingaquantitativemethod
AT tingkaileung disclosingcriticalvoicefeaturesfordiscriminatingbetweendepressionandinsomniaapreliminarystudyfordevelopingaquantitativemethod
AT yungpingliu disclosingcriticalvoicefeaturesfordiscriminatingbetweendepressionandinsomniaapreliminarystudyfordevelopingaquantitativemethod
AT kaironghu disclosingcriticalvoicefeaturesfordiscriminatingbetweendepressionandinsomniaapreliminarystudyfordevelopingaquantitativemethod