The many faces of intracranial tuberculosis: atypical presentations on MRI—a descriptive observational cohort study
Abstract Background Atypical MRI findings of cranial tuberculosis can lead to prolonged delay in diagnosis resulting in high costs to evaluate for alternative diagnoses. The aim of this study was to describe a series of cranial tuberculosis patients with spectrum of MRI features, other than hydrocep...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2023-07-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43055-023-01061-6 |
| _version_ | 1797784683595956224 |
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| author | Ishan Kumar Shashank Shekhar Tanya Yadav Priyanka Aggarwal Pramod Kumar Singh Ram C. Shukla Ashish Verma |
| author_facet | Ishan Kumar Shashank Shekhar Tanya Yadav Priyanka Aggarwal Pramod Kumar Singh Ram C. Shukla Ashish Verma |
| author_sort | Ishan Kumar |
| collection | DOAJ |
| description | Abstract Background Atypical MRI findings of cranial tuberculosis can lead to prolonged delay in diagnosis resulting in high costs to evaluate for alternative diagnoses. The aim of this study was to describe a series of cranial tuberculosis patients with spectrum of MRI features, other than hydrocephalus, parenchymal tuberculomas, and leptomeningeal thickening. The final diagnosis was made based on CSF findings, clinical findings, and/or marked improvement after antitubercular treatment. Results A total of 39 patients met the inclusion criteria and were diagnosed with vasculitis (n = 15), tubercular abscess (n = 5), miliary tuberculosis (n = 3), tubercular cerebritis (n = 9), sellar and parasellar tuberculosis (n = 7), mass forming tuberculosis (n = 1), choroid plexitis (n = 2), and intraventricular tuberculomas (n = 1). Conclusion A significant number of patients of cranial tuberculosis can have variable presentations and may be misdiagnosed. This analysis helps to reinvestigate the spectrum of MRI findings. |
| first_indexed | 2024-03-13T00:43:24Z |
| format | Article |
| id | doaj.art-32d7ead514cc43e0851a7973cf5e5179 |
| institution | Directory Open Access Journal |
| issn | 2090-4762 |
| language | English |
| last_indexed | 2024-03-13T00:43:24Z |
| publishDate | 2023-07-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-32d7ead514cc43e0851a7973cf5e51792023-07-09T11:09:30ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622023-07-0154111610.1186/s43055-023-01061-6The many faces of intracranial tuberculosis: atypical presentations on MRI—a descriptive observational cohort studyIshan Kumar0Shashank Shekhar1Tanya Yadav2Priyanka Aggarwal3Pramod Kumar Singh4Ram C. Shukla5Ashish Verma6Departments of Radiodiagnosis and Pediatrics, Institute of Medical Sciences, Banaras Hindu UniversityDepartments of Radiodiagnosis and Pediatrics, Institute of Medical Sciences, Banaras Hindu UniversityDepartments of Radiodiagnosis and Pediatrics, Institute of Medical Sciences, Banaras Hindu UniversityDepartments of Radiodiagnosis and Pediatrics, Institute of Medical Sciences, Banaras Hindu UniversityDepartments of Radiodiagnosis and Pediatrics, Institute of Medical Sciences, Banaras Hindu UniversityDepartments of Radiodiagnosis and Pediatrics, Institute of Medical Sciences, Banaras Hindu UniversityDepartments of Radiodiagnosis and Pediatrics, Institute of Medical Sciences, Banaras Hindu UniversityAbstract Background Atypical MRI findings of cranial tuberculosis can lead to prolonged delay in diagnosis resulting in high costs to evaluate for alternative diagnoses. The aim of this study was to describe a series of cranial tuberculosis patients with spectrum of MRI features, other than hydrocephalus, parenchymal tuberculomas, and leptomeningeal thickening. The final diagnosis was made based on CSF findings, clinical findings, and/or marked improvement after antitubercular treatment. Results A total of 39 patients met the inclusion criteria and were diagnosed with vasculitis (n = 15), tubercular abscess (n = 5), miliary tuberculosis (n = 3), tubercular cerebritis (n = 9), sellar and parasellar tuberculosis (n = 7), mass forming tuberculosis (n = 1), choroid plexitis (n = 2), and intraventricular tuberculomas (n = 1). Conclusion A significant number of patients of cranial tuberculosis can have variable presentations and may be misdiagnosed. This analysis helps to reinvestigate the spectrum of MRI findings.https://doi.org/10.1186/s43055-023-01061-6TuberculosisBrainMRIImaging spectrum |
| spellingShingle | Ishan Kumar Shashank Shekhar Tanya Yadav Priyanka Aggarwal Pramod Kumar Singh Ram C. Shukla Ashish Verma The many faces of intracranial tuberculosis: atypical presentations on MRI—a descriptive observational cohort study The Egyptian Journal of Radiology and Nuclear Medicine Tuberculosis Brain MRI Imaging spectrum |
| title | The many faces of intracranial tuberculosis: atypical presentations on MRI—a descriptive observational cohort study |
| title_full | The many faces of intracranial tuberculosis: atypical presentations on MRI—a descriptive observational cohort study |
| title_fullStr | The many faces of intracranial tuberculosis: atypical presentations on MRI—a descriptive observational cohort study |
| title_full_unstemmed | The many faces of intracranial tuberculosis: atypical presentations on MRI—a descriptive observational cohort study |
| title_short | The many faces of intracranial tuberculosis: atypical presentations on MRI—a descriptive observational cohort study |
| title_sort | many faces of intracranial tuberculosis atypical presentations on mri a descriptive observational cohort study |
| topic | Tuberculosis Brain MRI Imaging spectrum |
| url | https://doi.org/10.1186/s43055-023-01061-6 |
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