Molecular Mechanisms of Curcumin Renoprotection in Experimental Acute Renal Injury

Molecular Mechanisms of Curcumin Renoprotection in Experimental Acute Renal Injury

As a highly perfused organ, the kidney is especially sensitive to ischemia and reperfusion. Ischemia-reperfusion (IR)-induced acute kidney injury (AKI) has a high incidence during the perioperative period in the clinic and is an important link in ischemic acute renal failure (IARF). Therefore, IR-in...

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Bibliographic Details
Main Authors: Youling Fan, Hongtao Chen, Huihua Peng, Fang Huang, Jiying Zhong, Jun Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Pharmacology
Subjects:
acute kidney injury
curcumin
APPL1
apoptosis
Akt
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00912/full

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