Long-Lived αMUPA Mice Show Attenuation of Cardiac Aging and Leptin-Dependent Cardioprotection.

Long-Lived αMUPA Mice Show Attenuation of Cardiac Aging and Leptin-Dependent Cardioprotection.

αMUPA transgenic mice spontaneously consume less food compared with their wild type (WT) ancestors due to endogenously increased levels of the satiety hormone leptin. αMUPA mice share many benefits with mice under caloric restriction (CR) including an extended life span. To understand mechanisms lin...

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Bibliographic Details
Main Authors: Esther Levy, Ran Kornowski, Reut Gavrieli, Ilana Fratty, Gabriel Greenberg, Maayan Waldman, Einat Birk, Asher Shainberg, Amit Akirov, Ruth Miskin, Edith Hochhauser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4681471?pdf=render

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