Effects of Curcumin and Ferulic Acid on the Folding of Amyloid-β Peptide

Effects of Curcumin and Ferulic Acid on the Folding of Amyloid-β Peptide

The polyphenols curcumin (CU) and ferulic acid (FA) are able to inhibit the aggregation of amyloid-β (Aβ) peptide with different strengths. CU is a strong inhibitor while FA is a weaker one. In the present study, we examine the effects of CU and FA on the folding process of an Aβ monomer by 1 µs mol...

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Bibliographic Details
Main Authors:	Evdokiya Salamanova, Mariyana Atanasova, Ivan Dimitrov, Irini Doytchinova
Format:	Article
Language:	English
Published:	MDPI AG 2021-05-01
Series:	Molecules
Subjects:	curcumin ferulic acid amyloid-β peptide molecular dynamics simulation folding secondary structure
Online Access:	https://www.mdpi.com/1420-3049/26/9/2815

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