Gene Silencing of Transferrin-1 Receptor as a Potential Therapeutic Target for Human Follicular and Anaplastic Thyroid Cancer

Gene Silencing of Transferrin-1 Receptor as a Potential Therapeutic Target for Human Follicular and Anaplastic Thyroid Cancer

Herein, we assess the gene expression changes activated in thyroid tumors through a computational approach, using the MapReduce algorithm. Through this predictive analysis, we identified the TfR1 gene as a critical mediator of thyroid tumor progression. Then, we investigated the effect of TfR1 gene...

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Bibliographic Details
Main Authors:	Agata Campisi, Roberta Bonfanti, Giuseppina Raciti, Gabriele Bonaventura, Laura Legnani, Gaetano Magro, Marzio Pennisi, Giulia Russo, Maria Assunta Chiacchio, Francesco Pappalardo, Rosalba Parenti
Format:	Article
Language:	English
Published:	Elsevier 2020-03-01
Series:	Molecular Therapy: Oncolytics
Online Access:	http://www.sciencedirect.com/science/article/pii/S2372770520300097

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