The role of dermal regeneration template in anterior abdominal wall defect after burst abdomen: A case report in acute graft versus host disease of the gastrointestinal tract in aplastic anemia
Acute graft-versus-host disease of the gastrointestinal tract (GI-aGVHD) is a rare condition, often requiring multiple laparotomies, ultimately leading to a burst abdomen. We report the successful use of a dermal regeneration template (DRT), combined with negative pressure wound therapy (NPWT) and s...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Journal of Indian Association of Pediatric Surgeons |
| Subjects: | |
| Online Access: | http://www.jiaps.com/article.asp?issn=0971-9261;year=2022;volume=27;issue=6;spage=760;epage=763;aulast=Vasudevan |
| _version_ | 1828270888814903296 |
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| author | Srikanth Vasudevan Harish Kumar Kabilan Krithika Jagadish Y N Anantheswar Ashok Basur Chandrappa Dinkar Sreekumar Annika Marwah |
| author_facet | Srikanth Vasudevan Harish Kumar Kabilan Krithika Jagadish Y N Anantheswar Ashok Basur Chandrappa Dinkar Sreekumar Annika Marwah |
| author_sort | Srikanth Vasudevan |
| collection | DOAJ |
| description | Acute graft-versus-host disease of the gastrointestinal tract (GI-aGVHD) is a rare condition, often requiring multiple laparotomies, ultimately leading to a burst abdomen. We report the successful use of a dermal regeneration template (DRT), combined with negative pressure wound therapy (NPWT) and skin grafts, to reconstruct the abdominal skin in an 11-year-old boy. The patient was a case of aplastic anemia, who underwent bone marrow transfers, the first of which failed and the second one was successful. He eventually developed gastrointestinal GVHD. Repeated laparotomies were done for recurrent intestinal obstruction. He also underwent resection anastomosis and end ileostomy, after which he developed an anterior abdominal wall defect due to a burst abdomen. After 12 months of management with multiple dressings, NPWT, and DRT, a stable coverage was achieved, without skin retraction. We report our experience in anterior abdominal wall reconstruction in a case of GI-aGVHD using DRT |
| first_indexed | 2024-04-13T05:47:30Z |
| format | Article |
| id | doaj.art-32e0cb5cb4714e5896e5c6a3cc2f250a |
| institution | Directory Open Access Journal |
| issn | 0971-9261 1998-3891 |
| language | English |
| last_indexed | 2024-04-13T05:47:30Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Indian Association of Pediatric Surgeons |
| spelling | doaj.art-32e0cb5cb4714e5896e5c6a3cc2f250a2022-12-22T02:59:55ZengWolters Kluwer Medknow PublicationsJournal of Indian Association of Pediatric Surgeons0971-92611998-38912022-01-0127676076310.4103/jiaps.jiaps_20_22The role of dermal regeneration template in anterior abdominal wall defect after burst abdomen: A case report in acute graft versus host disease of the gastrointestinal tract in aplastic anemiaSrikanth VasudevanHarish Kumar KabilanKrithika JagadishY N AnantheswarAshok Basur ChandrappaDinkar SreekumarAnnika MarwahAcute graft-versus-host disease of the gastrointestinal tract (GI-aGVHD) is a rare condition, often requiring multiple laparotomies, ultimately leading to a burst abdomen. We report the successful use of a dermal regeneration template (DRT), combined with negative pressure wound therapy (NPWT) and skin grafts, to reconstruct the abdominal skin in an 11-year-old boy. The patient was a case of aplastic anemia, who underwent bone marrow transfers, the first of which failed and the second one was successful. He eventually developed gastrointestinal GVHD. Repeated laparotomies were done for recurrent intestinal obstruction. He also underwent resection anastomosis and end ileostomy, after which he developed an anterior abdominal wall defect due to a burst abdomen. After 12 months of management with multiple dressings, NPWT, and DRT, a stable coverage was achieved, without skin retraction. We report our experience in anterior abdominal wall reconstruction in a case of GI-aGVHD using DRThttp://www.jiaps.com/article.asp?issn=0971-9261;year=2022;volume=27;issue=6;spage=760;epage=763;aulast=Vasudevandermal regeneration templategastrointestinal graft-versus-host diseaselaparotomy wound |
| spellingShingle | Srikanth Vasudevan Harish Kumar Kabilan Krithika Jagadish Y N Anantheswar Ashok Basur Chandrappa Dinkar Sreekumar Annika Marwah The role of dermal regeneration template in anterior abdominal wall defect after burst abdomen: A case report in acute graft versus host disease of the gastrointestinal tract in aplastic anemia Journal of Indian Association of Pediatric Surgeons dermal regeneration template gastrointestinal graft-versus-host disease laparotomy wound |
| title | The role of dermal regeneration template in anterior abdominal wall defect after burst abdomen: A case report in acute graft versus host disease of the gastrointestinal tract in aplastic anemia |
| title_full | The role of dermal regeneration template in anterior abdominal wall defect after burst abdomen: A case report in acute graft versus host disease of the gastrointestinal tract in aplastic anemia |
| title_fullStr | The role of dermal regeneration template in anterior abdominal wall defect after burst abdomen: A case report in acute graft versus host disease of the gastrointestinal tract in aplastic anemia |
| title_full_unstemmed | The role of dermal regeneration template in anterior abdominal wall defect after burst abdomen: A case report in acute graft versus host disease of the gastrointestinal tract in aplastic anemia |
| title_short | The role of dermal regeneration template in anterior abdominal wall defect after burst abdomen: A case report in acute graft versus host disease of the gastrointestinal tract in aplastic anemia |
| title_sort | role of dermal regeneration template in anterior abdominal wall defect after burst abdomen a case report in acute graft versus host disease of the gastrointestinal tract in aplastic anemia |
| topic | dermal regeneration template gastrointestinal graft-versus-host disease laparotomy wound |
| url | http://www.jiaps.com/article.asp?issn=0971-9261;year=2022;volume=27;issue=6;spage=760;epage=763;aulast=Vasudevan |
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