Specific Combinations of Inflammatory, Angiogenesis and Vascular Integrity Biomarkers Are Associated with Clinical Severity, Coma and Mortality in Beninese Children with Plasmodium Falciparum Malaria

Specific Combinations of Inflammatory, Angiogenesis and Vascular Integrity Biomarkers Are Associated with Clinical Severity, Coma and Mortality in Beninese Children with Plasmodium Falciparum Malaria

Malaria-related deaths could be prevented if powerful diagnostic and reliable prognostic biomarkers were available to allow rapid prediction of the clinical severity allowing adequate treatment. Using quantitative ELISA, we assessed the plasma concentrations of Procalcitonin, Pentraxine-3, Ang-2, sT...

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Bibliographic Details
Main Authors: Bernard Tornyigah, Samuel Odarkwei Blankson, Rafiou Adamou, Azizath Moussiliou, Lauriane Rietmeyer, Patrick Tettey, Liliane Dikroh, Bernard Addo, Helena Lamptey, Maroufou J. Alao, Annick Amoussou, Caroline Padounou, Christian Roussilhon, Sylvie Pons, Benedicta Ayiedu Mensah, Nicaise Tuikue Ndam, Rachida Tahar
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Diagnostics
Subjects:
cerebral malaria
biomarkers
sICAM-1
EPCR
PTX3
PCT
Online Access:https://www.mdpi.com/2075-4418/12/2/524

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