Cross-talk between microglia and neurons regulates HIV latency.
Despite effective antiretroviral therapy (ART), HIV-associated neurocognitive disorders (HAND) are found in nearly one-third of patients. Using a cellular co-culture system including neurons and human microglia infected with HIV (hμglia/HIV), we investigated the hypothesis that HIV-dependent neurolo...
Main Authors: | David Alvarez-Carbonell, Fengchun Ye, Nirmala Ramanath, Yoelvis Garcia-Mesa, Pamela E Knapp, Kurt F Hauser, Jonathan Karn |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-12-01
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Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1008249 |
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