Prognosis of COVID-19 in the middle eastern population, knowns and unknowns
Since its emergence in China in 2019, the SARS-CoV-2 virus has affected all countries worldwide. The virus is easily transmitted from one person to another via infected aerosols or contaminated surfaces. Unlike its counterparts, the prognosis of COVID-19 ranges from asymptomatic to critical disease...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Microbiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2022.974205/full |
| _version_ | 1797999733710520320 |
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| author | Iman Dandachi Waleed Aljabr |
| author_facet | Iman Dandachi Waleed Aljabr |
| author_sort | Iman Dandachi |
| collection | DOAJ |
| description | Since its emergence in China in 2019, the SARS-CoV-2 virus has affected all countries worldwide. The virus is easily transmitted from one person to another via infected aerosols or contaminated surfaces. Unlike its counterparts, the prognosis of COVID-19 ranges from asymptomatic to critical disease or death. Several factors play a role in determining the severity of the disease in infected patients. Among others, is the pre-existence of an underlying medical condition such as diabetes, cancer, and others. Furthermore, although children are less prone to the severe form of the COVID-19 disease, they require attention due to the report of many atypical presentations of the infection, post-asymptomatic exposure. In the Middle East, little is known about the prognosis of the SARS-CoV-2 infection in high-risk categories, notably patients with diabetes, cancer, and pregnant women. The aim of this review is to summarize the current knowledge about this group of population in the middle eastern region as well as to highlight the gap in the literature. We have found that the majority of the papers were from the Gulf countries. Although, few studies were conducted; high-risk patients appear to have an increased risk of morbidity and mortality from COVID-19 compared to their counterparts. Higher levels of inflammatory markers, C-reactive protein, erythrocyte sedimentation rate, D-dimer, and ferritin levels were also observed. Children are often asymptomatic or present with atypical presentations. More studies should be conducted to determine the clinical biomarkers of COVID-19 in high-risk categories to help in patient risk stratification and management in the middle eastern population. |
| first_indexed | 2024-04-11T11:09:27Z |
| format | Article |
| id | doaj.art-32e7d50444d34905b7aff18e5ced974d |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-04-11T11:09:27Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-32e7d50444d34905b7aff18e5ced974d2022-12-22T04:27:38ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2022-08-011310.3389/fmicb.2022.974205974205Prognosis of COVID-19 in the middle eastern population, knowns and unknownsIman DandachiWaleed AljabrSince its emergence in China in 2019, the SARS-CoV-2 virus has affected all countries worldwide. The virus is easily transmitted from one person to another via infected aerosols or contaminated surfaces. Unlike its counterparts, the prognosis of COVID-19 ranges from asymptomatic to critical disease or death. Several factors play a role in determining the severity of the disease in infected patients. Among others, is the pre-existence of an underlying medical condition such as diabetes, cancer, and others. Furthermore, although children are less prone to the severe form of the COVID-19 disease, they require attention due to the report of many atypical presentations of the infection, post-asymptomatic exposure. In the Middle East, little is known about the prognosis of the SARS-CoV-2 infection in high-risk categories, notably patients with diabetes, cancer, and pregnant women. The aim of this review is to summarize the current knowledge about this group of population in the middle eastern region as well as to highlight the gap in the literature. We have found that the majority of the papers were from the Gulf countries. Although, few studies were conducted; high-risk patients appear to have an increased risk of morbidity and mortality from COVID-19 compared to their counterparts. Higher levels of inflammatory markers, C-reactive protein, erythrocyte sedimentation rate, D-dimer, and ferritin levels were also observed. Children are often asymptomatic or present with atypical presentations. More studies should be conducted to determine the clinical biomarkers of COVID-19 in high-risk categories to help in patient risk stratification and management in the middle eastern population.https://www.frontiersin.org/articles/10.3389/fmicb.2022.974205/fullSARS-CoV-2diabetescancerchildrenpregnancy |
| spellingShingle | Iman Dandachi Waleed Aljabr Prognosis of COVID-19 in the middle eastern population, knowns and unknowns Frontiers in Microbiology SARS-CoV-2 diabetes cancer children pregnancy |
| title | Prognosis of COVID-19 in the middle eastern population, knowns and unknowns |
| title_full | Prognosis of COVID-19 in the middle eastern population, knowns and unknowns |
| title_fullStr | Prognosis of COVID-19 in the middle eastern population, knowns and unknowns |
| title_full_unstemmed | Prognosis of COVID-19 in the middle eastern population, knowns and unknowns |
| title_short | Prognosis of COVID-19 in the middle eastern population, knowns and unknowns |
| title_sort | prognosis of covid 19 in the middle eastern population knowns and unknowns |
| topic | SARS-CoV-2 diabetes cancer children pregnancy |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2022.974205/full |
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