Voltammetric estimation of residual nitroxynil in food products using carbon paste electrode
Abstract A simple and sensitive voltammetric method was developed and validated for the recognition of the veterinary drug nitroxynil (NTX). The method is based on studying its voltammetric behavior at a carbon paste electrode. Square wave voltammetry (SWV) was successfully applied in this study. Th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2022-08-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-18305-6 |
| _version_ | 1817999021500792832 |
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| author | Mohamed M. Salim Sally Ashraf Heba M. Hashem Fathalla Belal |
| author_facet | Mohamed M. Salim Sally Ashraf Heba M. Hashem Fathalla Belal |
| author_sort | Mohamed M. Salim |
| collection | DOAJ |
| description | Abstract A simple and sensitive voltammetric method was developed and validated for the recognition of the veterinary drug nitroxynil (NTX). The method is based on studying its voltammetric behavior at a carbon paste electrode. Square wave voltammetry (SWV) was successfully applied in this study. The anodic peak current obtained was a linear function of NTX concentration in Britton Robinson buffer of pH 3 over the range of 3.9 × 10–6–1.0 × 10−4 M with lower detection and quantitation limits of 3.1 × 10–7 and 9.4 × 10–7 M, respectively. The proposed method was first applied to the assessment of the drug in commercial vials. The method was further used to monitor the residual amounts of the drug in bovine meat, kidney, fat, and milk samples. The results obtained were favourably compared with those given by reference method. The interference likely to be introduced by co-administered drugs was evaluated. The electrode reaction was elucidated, and electron transfer kinetics were studied. |
| first_indexed | 2024-04-14T03:02:19Z |
| format | Article |
| id | doaj.art-32eaac4ddfd240189ae323d069c2231f |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-14T03:02:19Z |
| publishDate | 2022-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-32eaac4ddfd240189ae323d069c2231f2022-12-22T02:15:52ZengNature PortfolioScientific Reports2045-23222022-08-0112111010.1038/s41598-022-18305-6Voltammetric estimation of residual nitroxynil in food products using carbon paste electrodeMohamed M. Salim0Sally Ashraf1Heba M. Hashem2Fathalla Belal3Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Mansoura UniversityPharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Mansoura UniversityPharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Mansoura UniversityPharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Mansoura UniversityAbstract A simple and sensitive voltammetric method was developed and validated for the recognition of the veterinary drug nitroxynil (NTX). The method is based on studying its voltammetric behavior at a carbon paste electrode. Square wave voltammetry (SWV) was successfully applied in this study. The anodic peak current obtained was a linear function of NTX concentration in Britton Robinson buffer of pH 3 over the range of 3.9 × 10–6–1.0 × 10−4 M with lower detection and quantitation limits of 3.1 × 10–7 and 9.4 × 10–7 M, respectively. The proposed method was first applied to the assessment of the drug in commercial vials. The method was further used to monitor the residual amounts of the drug in bovine meat, kidney, fat, and milk samples. The results obtained were favourably compared with those given by reference method. The interference likely to be introduced by co-administered drugs was evaluated. The electrode reaction was elucidated, and electron transfer kinetics were studied.https://doi.org/10.1038/s41598-022-18305-6 |
| spellingShingle | Mohamed M. Salim Sally Ashraf Heba M. Hashem Fathalla Belal Voltammetric estimation of residual nitroxynil in food products using carbon paste electrode Scientific Reports |
| title | Voltammetric estimation of residual nitroxynil in food products using carbon paste electrode |
| title_full | Voltammetric estimation of residual nitroxynil in food products using carbon paste electrode |
| title_fullStr | Voltammetric estimation of residual nitroxynil in food products using carbon paste electrode |
| title_full_unstemmed | Voltammetric estimation of residual nitroxynil in food products using carbon paste electrode |
| title_short | Voltammetric estimation of residual nitroxynil in food products using carbon paste electrode |
| title_sort | voltammetric estimation of residual nitroxynil in food products using carbon paste electrode |
| url | https://doi.org/10.1038/s41598-022-18305-6 |
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