Passion fruit peel pectin/chitosan based antibacterial films incorporated with biosynthesized silver nanoparticles for wound healing application
Antimicrobial pectin/chitosan composite films have potential as wound dressing and food packaging. However, almost biofilms were synthesized through chemical routes, causing eco-unfriendliness, and negative impacts on the environment and human health. Green synthesis of composite films incorporating...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-04-01
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| Series: | Alexandria Engineering Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1110016823000984 |
| _version_ | 1797847685477171200 |
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| author | Thuy Thi Thanh Nguyen Ngan Thi Kim Tran Tu Quoc Le Tuyet Thi Anh Nguyen Lan Thi My Nguyen Thuan Van Tran |
| author_facet | Thuy Thi Thanh Nguyen Ngan Thi Kim Tran Tu Quoc Le Tuyet Thi Anh Nguyen Lan Thi My Nguyen Thuan Van Tran |
| author_sort | Thuy Thi Thanh Nguyen |
| collection | DOAJ |
| description | Antimicrobial pectin/chitosan composite films have potential as wound dressing and food packaging. However, almost biofilms were synthesized through chemical routes, causing eco-unfriendliness, and negative impacts on the environment and human health. Green synthesis of composite films incorporating with biosynthesized AgNPs is therefore necessary to enhance mechanical and antimicrobial activities. This study focused on the influence of biosynthesized AgNPs on characteristics of passion fruit peel pectin/chitosan (P/CH) biofilms. Characterization, mechanical, antimicrobial activities of P/CH/AgNPs biofilms were evaluated. Incorporating AgNPs into P/CH-based films significantly exerted apparent color and optical properties of biofilms. As AgNPs concentration increased, P/CH/AgNPs biofilms had higher water content (20.1%), better water vapor permeability (1.28 × 10–9 g/mm h Pa), but lower mechanical, water solubility (43.98%), swelling (630.29 ± 11.79%) indexes. P/CH/AgNPs biofilms exhibited outstanding antibacterial properties against S. aureus, B. cereus, P. aeruginosa, K. pneumonia. As expected, in vivo results consolidated the evidence of excellent wound closure (100%) of P/CH/AgNPs biofilms after 15 days. Our findings recommend P/CH/AgNPs antibacterial biofilms have promising biomedical applications. |
| first_indexed | 2024-04-09T18:16:25Z |
| format | Article |
| id | doaj.art-32eb5a15d8284f9f9885355146b755af |
| institution | Directory Open Access Journal |
| issn | 1110-0168 |
| language | English |
| last_indexed | 2024-04-09T18:16:25Z |
| publishDate | 2023-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Alexandria Engineering Journal |
| spelling | doaj.art-32eb5a15d8284f9f9885355146b755af2023-04-13T04:26:17ZengElsevierAlexandria Engineering Journal1110-01682023-04-0169419430Passion fruit peel pectin/chitosan based antibacterial films incorporated with biosynthesized silver nanoparticles for wound healing applicationThuy Thi Thanh Nguyen0Ngan Thi Kim Tran1Tu Quoc Le2Tuyet Thi Anh Nguyen3Lan Thi My Nguyen4Thuan Van Tran5Faculty of Science, Nong Lam University Ho Chi Minh City, Ho Chi Minh City 700000, Viet Nam; Corresponding authors at: Institute of Applied Technology and Sustainable Development, Nguyen Tat Thanh University, 298-300A, Nguyen Tat Thanh, District 4, Ho Chi Minh City 755414, Viet Nam (Thuan Van Tran).Faculty of Science, Nong Lam University Ho Chi Minh City, Ho Chi Minh City 700000, Viet NamFaculty of Science, Nong Lam University Ho Chi Minh City, Ho Chi Minh City 700000, Viet NamUniversity of Science, Viet Nam National University Ho Chi Minh City, Ho Chi Minh City 700000, Viet NamUniversity of Science, Viet Nam National University Ho Chi Minh City, Ho Chi Minh City 700000, Viet NamInstitute of Applied Technology and Sustainable Development, Nguyen Tat Thanh University, 298-300A, Nguyen Tat Thanh, District 4, Ho Chi Minh City 755414, Viet Nam; NTT High-Tech Institute, Nguyen Tat Thanh University, 298-300A, Nguyen Tat Thanh, District, 4, Ho Chi Minh City 755414, Viet Nam; Corresponding authors at: Institute of Applied Technology and Sustainable Development, Nguyen Tat Thanh University, 298-300A, Nguyen Tat Thanh, District 4, Ho Chi Minh City 755414, Viet Nam (Thuan Van Tran).Antimicrobial pectin/chitosan composite films have potential as wound dressing and food packaging. However, almost biofilms were synthesized through chemical routes, causing eco-unfriendliness, and negative impacts on the environment and human health. Green synthesis of composite films incorporating with biosynthesized AgNPs is therefore necessary to enhance mechanical and antimicrobial activities. This study focused on the influence of biosynthesized AgNPs on characteristics of passion fruit peel pectin/chitosan (P/CH) biofilms. Characterization, mechanical, antimicrobial activities of P/CH/AgNPs biofilms were evaluated. Incorporating AgNPs into P/CH-based films significantly exerted apparent color and optical properties of biofilms. As AgNPs concentration increased, P/CH/AgNPs biofilms had higher water content (20.1%), better water vapor permeability (1.28 × 10–9 g/mm h Pa), but lower mechanical, water solubility (43.98%), swelling (630.29 ± 11.79%) indexes. P/CH/AgNPs biofilms exhibited outstanding antibacterial properties against S. aureus, B. cereus, P. aeruginosa, K. pneumonia. As expected, in vivo results consolidated the evidence of excellent wound closure (100%) of P/CH/AgNPs biofilms after 15 days. Our findings recommend P/CH/AgNPs antibacterial biofilms have promising biomedical applications.http://www.sciencedirect.com/science/article/pii/S1110016823000984PectinChitosanAntibacterial filmsPassion fruit peelSilver nanoparticlesWound healing |
| spellingShingle | Thuy Thi Thanh Nguyen Ngan Thi Kim Tran Tu Quoc Le Tuyet Thi Anh Nguyen Lan Thi My Nguyen Thuan Van Tran Passion fruit peel pectin/chitosan based antibacterial films incorporated with biosynthesized silver nanoparticles for wound healing application Alexandria Engineering Journal Pectin Chitosan Antibacterial films Passion fruit peel Silver nanoparticles Wound healing |
| title | Passion fruit peel pectin/chitosan based antibacterial films incorporated with biosynthesized silver nanoparticles for wound healing application |
| title_full | Passion fruit peel pectin/chitosan based antibacterial films incorporated with biosynthesized silver nanoparticles for wound healing application |
| title_fullStr | Passion fruit peel pectin/chitosan based antibacterial films incorporated with biosynthesized silver nanoparticles for wound healing application |
| title_full_unstemmed | Passion fruit peel pectin/chitosan based antibacterial films incorporated with biosynthesized silver nanoparticles for wound healing application |
| title_short | Passion fruit peel pectin/chitosan based antibacterial films incorporated with biosynthesized silver nanoparticles for wound healing application |
| title_sort | passion fruit peel pectin chitosan based antibacterial films incorporated with biosynthesized silver nanoparticles for wound healing application |
| topic | Pectin Chitosan Antibacterial films Passion fruit peel Silver nanoparticles Wound healing |
| url | http://www.sciencedirect.com/science/article/pii/S1110016823000984 |
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