Molecular Genetics of Pre-B Acute Lymphoblastic Leukemia Sister Cell Lines during Disease Progression

Molecular Genetics of Pre-B Acute Lymphoblastic Leukemia Sister Cell Lines during Disease Progression

For many years, immortalized tumor cell lines have been used as reliable tools to understand the function of oncogenes and tumor suppressor genes. Today, we know that tumors can comprise subclones with common and with subclone-specific genetic alterations. We sequenced DNA and RNA of sequential sist...

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Bibliographic Details
Main Authors: Hilmar Quentmeier, Claudia Pommerenke, Hans G. Drexler
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Current Issues in Molecular Biology
Subjects:
<i>MEF2D-BCL9</i>
<i>PAX5</i> R38H
pre-B-ALL
Online Access:https://www.mdpi.com/1467-3045/43/3/149

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