Molecular Genetics of Pre-B Acute Lymphoblastic Leukemia Sister Cell Lines during Disease Progression
For many years, immortalized tumor cell lines have been used as reliable tools to understand the function of oncogenes and tumor suppressor genes. Today, we know that tumors can comprise subclones with common and with subclone-specific genetic alterations. We sequenced DNA and RNA of sequential sist...
Main Authors: | Hilmar Quentmeier, Claudia Pommerenke, Hans G. Drexler |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-11-01
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Series: | Current Issues in Molecular Biology |
Subjects: | |
Online Access: | https://www.mdpi.com/1467-3045/43/3/149 |
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