Atypical clinical and radiologic findings in a patient with brain metastatic lesions

We report the case of a 47-year-old man who was admitted to our clinic with an intractable headache, nausea, and sporadic vomiting, as well as speech difficulties and a ‘floating’ sensation. This man had no prior medical history. MRI of the brain showed evidence of over 20 supra- and infratentorial...

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Main Authors: Eray Halil, Ekaterina Viteva, Georgi Vasilev, Krasimir Shukerski, Penka Atanassova
Format: Article
Language:English
Published: Pensoft Publishers 2023-10-01
Series:Folia Medica
Online Access:https://foliamedica.bg/article/84810/download/pdf/
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author Eray Halil
Ekaterina Viteva
Georgi Vasilev
Krasimir Shukerski
Penka Atanassova
author_facet Eray Halil
Ekaterina Viteva
Georgi Vasilev
Krasimir Shukerski
Penka Atanassova
author_sort Eray Halil
collection DOAJ
description We report the case of a 47-year-old man who was admitted to our clinic with an intractable headache, nausea, and sporadic vomiting, as well as speech difficulties and a ‘floating’ sensation. This man had no prior medical history. MRI of the brain showed evidence of over 20 supra- and infratentorial capsulated ring-enhancing lesions. All other paraclinical investigations done in our clinic were unremarkable and we excluded our first assumption of neurocysticercosis, as well as other parasitic infections. The patient was then referred to the Oral and Maxillofacial Surgery Clinic for an excisional biopsy of a submandibular formation, which was later verified to represent a lymph node metastasis from a poorly differentiated adenocarcinoma. A chest X-ray failed to demonstrate any significant pathology and the immunohistochemical constellation of the lymph node metastasis excluded the possibility of the primary tumor originating in the lung or the prostate. Due to the unresolved diagnostic query, a whole-body PET/CT was performed demonstrating a formation with malignant characteristics in the basal segment of the left lung, reaching the pleura and the left hilum, as well as solitary enlarged mesenteric and mediastinal lymph nodes. Following clinical consultations, it was determined that the patient was inoperable and chemotherapy and palliative CNS irradiation were recommended.
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spelling doaj.art-32f261c1e81f4807a8e2278aa1f5c0ac2023-11-02T09:11:13ZengPensoft PublishersFolia Medica1314-21432023-10-0165584484810.3897/folmed.65.e8481084810Atypical clinical and radiologic findings in a patient with brain metastatic lesionsEray Halil0Ekaterina Viteva1Georgi Vasilev2Krasimir Shukerski3Penka Atanassova4Medical University of PlovdivSt George University HospitalMedical University of PlovdivSt George University HospitalSt George University HospitalWe report the case of a 47-year-old man who was admitted to our clinic with an intractable headache, nausea, and sporadic vomiting, as well as speech difficulties and a ‘floating’ sensation. This man had no prior medical history. MRI of the brain showed evidence of over 20 supra- and infratentorial capsulated ring-enhancing lesions. All other paraclinical investigations done in our clinic were unremarkable and we excluded our first assumption of neurocysticercosis, as well as other parasitic infections. The patient was then referred to the Oral and Maxillofacial Surgery Clinic for an excisional biopsy of a submandibular formation, which was later verified to represent a lymph node metastasis from a poorly differentiated adenocarcinoma. A chest X-ray failed to demonstrate any significant pathology and the immunohistochemical constellation of the lymph node metastasis excluded the possibility of the primary tumor originating in the lung or the prostate. Due to the unresolved diagnostic query, a whole-body PET/CT was performed demonstrating a formation with malignant characteristics in the basal segment of the left lung, reaching the pleura and the left hilum, as well as solitary enlarged mesenteric and mediastinal lymph nodes. Following clinical consultations, it was determined that the patient was inoperable and chemotherapy and palliative CNS irradiation were recommended.https://foliamedica.bg/article/84810/download/pdf/
spellingShingle Eray Halil
Ekaterina Viteva
Georgi Vasilev
Krasimir Shukerski
Penka Atanassova
Atypical clinical and radiologic findings in a patient with brain metastatic lesions
Folia Medica
title Atypical clinical and radiologic findings in a patient with brain metastatic lesions
title_full Atypical clinical and radiologic findings in a patient with brain metastatic lesions
title_fullStr Atypical clinical and radiologic findings in a patient with brain metastatic lesions
title_full_unstemmed Atypical clinical and radiologic findings in a patient with brain metastatic lesions
title_short Atypical clinical and radiologic findings in a patient with brain metastatic lesions
title_sort atypical clinical and radiologic findings in a patient with brain metastatic lesions
url https://foliamedica.bg/article/84810/download/pdf/
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AT georgivasilev atypicalclinicalandradiologicfindingsinapatientwithbrainmetastaticlesions
AT krasimirshukerski atypicalclinicalandradiologicfindingsinapatientwithbrainmetastaticlesions
AT penkaatanassova atypicalclinicalandradiologicfindingsinapatientwithbrainmetastaticlesions