Maxadilan prevents apoptosis in iPS cells and shows no effects on the pluripotent state or karyotype.

Maxadilan prevents apoptosis in iPS cells and shows no effects on the pluripotent state or karyotype.

Pituitary adenylate cyclase-activating polypeptide (PACAP) is a structurally endogenous peptide with many biological roles. Maxadilan, a 61-amino acid vasodilatory peptide, specifically activates the PACAP type I receptor (PAC1). Although PAC1 has been identified in embryonic stem cells, little is k...

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Bibliographic Details
Main Authors: Zhiyi Zhao, Rongjie Yu, Jiayin Yang, Xiaofei Liu, Meihua Tan, Hongyang Li, Jiansu Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3311553?pdf=render

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