Echotexture analysis of L4 supraspinous enthesis in ankylosing spondylitis
Background: Enthesopathy is a main characteristic of ankylosing spondylitis (AS). However, ultrasonographic features of supraspinous enthesis in AS have not yet been reported. Methods: Forty-seven AS patients and 22 healthy individuals were enrolled and completed the study. L4 supraspinous entheses...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Journal of Medical Ultrasound |
| Subjects: | |
| Online Access: | http://www.jmuonline.org/article.asp?issn=0929-6441;year=2021;volume=29;issue=1;spage=32;epage=38;aulast= |
| _version_ | 1818734758699466752 |
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| author | Kuo-Lung Lai Fang-Chuan Kuo Chih-Wei Tseng Hsin-Hua Chen Yin-Yin Liao |
| author_facet | Kuo-Lung Lai Fang-Chuan Kuo Chih-Wei Tseng Hsin-Hua Chen Yin-Yin Liao |
| author_sort | Kuo-Lung Lai |
| collection | DOAJ |
| description | Background: Enthesopathy is a main characteristic of ankylosing spondylitis (AS). However, ultrasonographic features of supraspinous enthesis in AS have not yet been reported. Methods: Forty-seven AS patients and 22 healthy individuals were enrolled and completed the study. L4 supraspinous entheses were assessed through an ultrasound (US) unit with the participants in a lateral decubitus position. Entheseal echogenicity was interpreted upon inspection of the US image. An entheseal grayscale (GS) value determination, along with an echotexture analysis using a gray-level co-occurrence matrix algorithm, was performed. The thoracolumbar fascia just above the enthesis was also analyzed. An enthesis-to-fascia ratio (EFR) of each texture feature was used for the purpose of intergroup comparison. Results: The prevalence of abnormal entheseal echogenicity in the AS and healthy groups was 19.1% and 13.6%, respectively (P = 0.42). The AS group experienced a higher GS EFR (0.56 [0.10–1.08] vs. 0.40 [0.12–0.89], P = 0.007), higher contrast EFR (0.62 [0.15–1.23] vs. 0.49 [0.23–1.33], P = 0.049), higher variance EFR (0.44 [0.06–1.21] vs. 0.35 [0.13–1.10], P = 0.023), and lower homogeneity EFR (1.07 [0.97–1.27] vs. 1.11 [1.04–1.19], P = 0.011) in comparison to the healthy group. Conclusion: Echotexture analysis identified the subtle structural changes in L4 supraspinous enthesis in AS patients. It proved to be superior to the inspection method and may possess the potential for providing early detection of supraspinous enthesopathy in AS. |
| first_indexed | 2024-12-18T00:10:27Z |
| format | Article |
| id | doaj.art-32f736bd2bab45aa99aac0ab1854127b |
| institution | Directory Open Access Journal |
| issn | 0929-6441 2212-1552 |
| language | English |
| last_indexed | 2024-12-18T00:10:27Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Medical Ultrasound |
| spelling | doaj.art-32f736bd2bab45aa99aac0ab1854127b2022-12-21T21:27:41ZengWolters Kluwer Medknow PublicationsJournal of Medical Ultrasound0929-64412212-15522021-01-01291323810.4103/JMU.JMU_37_20Echotexture analysis of L4 supraspinous enthesis in ankylosing spondylitisKuo-Lung LaiFang-Chuan KuoChih-Wei TsengHsin-Hua ChenYin-Yin LiaoBackground: Enthesopathy is a main characteristic of ankylosing spondylitis (AS). However, ultrasonographic features of supraspinous enthesis in AS have not yet been reported. Methods: Forty-seven AS patients and 22 healthy individuals were enrolled and completed the study. L4 supraspinous entheses were assessed through an ultrasound (US) unit with the participants in a lateral decubitus position. Entheseal echogenicity was interpreted upon inspection of the US image. An entheseal grayscale (GS) value determination, along with an echotexture analysis using a gray-level co-occurrence matrix algorithm, was performed. The thoracolumbar fascia just above the enthesis was also analyzed. An enthesis-to-fascia ratio (EFR) of each texture feature was used for the purpose of intergroup comparison. Results: The prevalence of abnormal entheseal echogenicity in the AS and healthy groups was 19.1% and 13.6%, respectively (P = 0.42). The AS group experienced a higher GS EFR (0.56 [0.10–1.08] vs. 0.40 [0.12–0.89], P = 0.007), higher contrast EFR (0.62 [0.15–1.23] vs. 0.49 [0.23–1.33], P = 0.049), higher variance EFR (0.44 [0.06–1.21] vs. 0.35 [0.13–1.10], P = 0.023), and lower homogeneity EFR (1.07 [0.97–1.27] vs. 1.11 [1.04–1.19], P = 0.011) in comparison to the healthy group. Conclusion: Echotexture analysis identified the subtle structural changes in L4 supraspinous enthesis in AS patients. It proved to be superior to the inspection method and may possess the potential for providing early detection of supraspinous enthesopathy in AS.http://www.jmuonline.org/article.asp?issn=0929-6441;year=2021;volume=29;issue=1;spage=32;epage=38;aulast=ankylosing spondylitisechotexture analysisenthesopathysupraspinous enthesisultrasonography |
| spellingShingle | Kuo-Lung Lai Fang-Chuan Kuo Chih-Wei Tseng Hsin-Hua Chen Yin-Yin Liao Echotexture analysis of L4 supraspinous enthesis in ankylosing spondylitis Journal of Medical Ultrasound ankylosing spondylitis echotexture analysis enthesopathy supraspinous enthesis ultrasonography |
| title | Echotexture analysis of L4 supraspinous enthesis in ankylosing spondylitis |
| title_full | Echotexture analysis of L4 supraspinous enthesis in ankylosing spondylitis |
| title_fullStr | Echotexture analysis of L4 supraspinous enthesis in ankylosing spondylitis |
| title_full_unstemmed | Echotexture analysis of L4 supraspinous enthesis in ankylosing spondylitis |
| title_short | Echotexture analysis of L4 supraspinous enthesis in ankylosing spondylitis |
| title_sort | echotexture analysis of l4 supraspinous enthesis in ankylosing spondylitis |
| topic | ankylosing spondylitis echotexture analysis enthesopathy supraspinous enthesis ultrasonography |
| url | http://www.jmuonline.org/article.asp?issn=0929-6441;year=2021;volume=29;issue=1;spage=32;epage=38;aulast= |
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