Attenuation of stretch-induced arrhythmias following chemical ablation of Purkinje fibres, in isolated rabbit hearts

Attenuation of stretch-induced arrhythmias following chemical ablation of Purkinje fibres, in isolated rabbit hearts

Purkinje fibres (PFs) play an important role in some ventricular arrhythmias and acute ventricular stretch can evoke mechanically-induced arrhythmias. We tested whether Purkinje fibres, play a role in these arrhythmias. Pseudo-ECGs were recorded in isolated, Langendorff-perfused, rabbit hearts in wh...

Full description

Bibliographic Details
Main Authors:	Miriam Hurley, Richard Walton, Edward J. Vigmond, Michel Haïssaguerre, Olivier Bernus, Ed White
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-04-01
Series:	Frontiers in Physiology
Subjects:	ventricular arrhythmias stretch endocardium Purkinje fibres Lugol in silico modelling
Online Access:	https://www.frontiersin.org/articles/10.3389/fphys.2023.1154157/full

Similar Items

Endocardial role in arrhythmias induced by acute ventricular stretch and the involvement of Purkinje fibres, in isolated rat hearts
by: Miriam Hurley, et al.
Published: (2023-01-01)

Role of the Purkinje-Muscle Junction on the Ventricular Repolarization Heterogeneity in the Healthy and Ischemic Ovine Ventricular Myocardium
by: Marine E. Martinez, et al.
Published: (2018-06-01)

Editorial: Stretch and the heart: mechanoelectrical coupling and arrhythmias
by: Ewan Douglas Fowler, et al.
Published: (2023-08-01)

Why Ablation of Sites With Purkinje Activation Is Antiarrhythmic: The Interplay Between Fast Activation and Arrhythmogenesis
by: Ruben Coronel, et al.
Published: (2021-03-01)

Optical Imaging of Ventricular Action Potentials in a Torso Tank: A New Platform for Non-Invasive Electrocardiographic Imaging Validation
by: Laura R. Bear, et al.
Published: (2019-02-01)

Chemical ablation of the left ventricular endocardium reduces ventricular fibrillation inducibility in acute ischemic canine heart
by: Takashi Nitta, et al.
Published: (2024-04-01)

Computational framework for multiscale investigation of pro-arrhythmic mechanisms in the human cardiac Purkinje system
by: Trovato, C
Published: (2020)

Body Surface Mapping of Ventricular Repolarization Heterogeneity: An Ex-vivo Multiparameter Study
by: Marianna Meo, et al.
Published: (2020-08-01)

Simultaneous Non‐Invasive Epicardial and Endocardial Mapping in Patients With Brugada Syndrome: New Insights Into Arrhythmia Mechanisms
by: Boris Rudic, et al.
Published: (2016-10-01)

Electrophysiological features of repetitive focal Purkinje ventricular arrhythmias originating from the proximal cardiac conduction system
by: Shota Ikeda, et al.
Published: (2022-12-01)

Cross clinical-experimental-computational qualification of in silico drug trials on human cardiac purkinje cells for proarrhythmia risk prediction
by: Cristian Trovato, et al.
Published: (2022-10-01)

Syncope in a young man: Role of Purkinje fibres in idiopathic ventricular fibrillation
by: Claire A. Martin, PhD, et al.
Published: (2017-07-01)

The role of Purkinje-myocardial coupling during ventricular arrhythmia: a modeling study.
by: Elham Behradfar, et al.
Published: (2014-01-01)

Endocardial TRPC-6 Act as Atrial Mechanosensors and Load-Dependent Modulators of Endocardial/Myocardial Cross-Talk
by: Vesna Nikolova-Krstevski, PhD, et al.
Published: (2017-10-01)

Sex differences in ventricular arrhythmia: epidemiology, pathophysiology and catheter ablation
by: Philipp Krisai, et al.
Published: (2022-01-01)

Zinc's protective role against hydroxychloroquine-induced cardiac effects in adult male albino rats
by: Nihal A. Ibrahim, et al.
Published: (2023-08-01)

Effect of myocardial heterogeneity on ventricular electro-mechanical responses: a computational study
by: Nida Dusturia, et al.
Published: (2019-03-01)

Potential Application of Pulsed Field Ablation in Ventricular Arrhythmias
by: Jie Qiu, et al.
Published: (2023-04-01)

Endocardial Regulation of Cardiac Development
by: Lara Feulner, et al.
Published: (2022-04-01)

His-Purkinje system-related incessant ventricular tachycardia arising from the left coronary cusp
by: Eiji Sato, MD, et al.
Published: (2014-08-01)

Purkinje Cell Stripes and Long-term Depression at the Parallel Fiber-Purkinje Cell Synapse
by: Richard eHawkes
Published: (2014-03-01)

Oleuropein Attenuates Deltamethrin-induced Apoptosis in Rat Cerebellar Purkinje Neurons
by: Alireza Khalatbary, et al.
Published: (2015-10-01)

Electrophysiological and structural determinants of electrotonic modulation of repolarization by the activation sequence
by: Richard David Walton, et al.
Published: (2013-10-01)

Profound morphological and functional changes of rodent Purkinje cellsbetween the first and the second postnatal weeks: a metamorphosis?
by: Isabelle eDusart, et al.
Published: (2012-04-01)

A comprehensive framework for evaluation of high pacing frequency and arrhythmic optical mapping signals
by: Girish S. Ramlugun, et al.
Published: (2023-01-01)

MORPHOLOGICAL FEATURES OF HUMAN HEART VALVE APPARATUS AND EXPERIMENTAL ANIMALS IN THE NORMAL AND ON THE CONDITIONS OF THE INFLUENCE OF PATHOGENIC FACTORS
by: Roksolana Symivska
Published: (2018-12-01)

Transferences of Purkinje systems
by: W. F. Harris
Published: (2011-12-01)

Catheter ablation in patients with ventricular fibrillation by purkinje de-networking
by: Vanessa Sciacca, et al.
Published: (2022-09-01)

Estudo estereológico das células de Purkinje cerebelares submetidas à intoxicação alcoólica em ratos Wistar Stereologic study of the cerebellar Purkinje cells submitted to alcoholic intoxication in Wistar rats
by: Mara Ibis Rodrigues Apfel, et al.
Published: (2002-06-01)

Multiplexed coding by cerebellar Purkinje neurons
by: Sungho Hong, et al.
Published: (2016-07-01)

Stereological Estimation of Granule Cell Number and Purkinje Cell Volume in the Cerebellum of Noise-Exposed Young Rat
by: Mohammad Hosseini-Sharifabad, et al.
Published: (2015-07-01)

STEREOLOGICAL ANALYSIS OF HUMAN CEREBELLAR PURKINJE CELLS IN DEVELOPING BRAIN
by: Radmila Gudovic, et al.
Published: (2006-01-01)

Purkinje Cell-Specific Knockout of Tyrosine Hydroxylase Impairs Cognitive Behaviors
by: Timothy M. Locke, et al.
Published: (2020-07-01)

Fear conditioning-related changes in cerebellar Purkinje cell activities in goldfish
by: Yoshida Masayuki, et al.
Published: (2012-10-01)

Some Structural and Chemical Changes in Endocardial Endothelium of Rats in Emotional and Pain Stress Complicated by Hypercholesterolemia
by: Igor M Luchko, et al.
Published: (2017-06-01)

The Effect of Minocycline on Cerebellar Purkinje Neurons in Epileptic Rats
by: Rahim Golmohammadi, et al.
Published: (2019-01-01)

Motor learning of mice lacking cerebellar Purkinje cells
by: José A Armengol, et al.
Published: (2013-04-01)

Ankfy1 Is Involved in the Maintenance of Cerebellar Purkinje Cells
by: Liansheng Chang, et al.
Published: (2021-03-01)

Lugol como causa inusual de anafilaxia después de la colposcopia. Reporte de un caso clínico
by: Jimena Laiseca García
Published: (2023-01-01)

Pemanfaatan larutan lugol 2% untuk menanggulangi kasus kawin berulang pada sapi di Gampong Cot Madhi, Aceh Besar (Utilization 2% lugol’s solution to overcome the repeat breeding case of cows in Cot Madhi Village, Aceh Besar)
by: S Syafrudddin, et al.
Published: (2021-08-01)