m(6)A Modification of lncRNA NEAT1 Regulates Chronic Myelocytic Leukemia Progression via miR-766-5p/CDKN1A Axis

m(6)A Modification of lncRNA NEAT1 Regulates Chronic Myelocytic Leukemia Progression via miR-766-5p/CDKN1A Axis

BackgroundChronic myeloid leukemia (CML) is an acquired hematopoietic stem malignant disease originating from the myeloid system. Long non-coding RNAs (lncRNAs) have been widely explored in cancer tumorigenesis. However, their roles in CML remain largely unclear.MethodsThe peripheral blood mononucle...

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Bibliographic Details
Main Authors:	Fang-Yi Yao, Cui Zhao, Fang-Min Zhong, Ting-Yu Qin, Fang Wen, Mei-Yong Li, Jing Liu, Bo Huang, Xiao-Zhong Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-07-01
Series:	Frontiers in Oncology
Subjects:	chronic myeloid leukemia NEAT1 miR-766-5p CDKN1A N6-methyladenosine (m6A) modification METTL3
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2021.679634/full

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