Cocaine enhances HIV-1 replication in CD4+ T cells by down-regulating MiR-125b.

Cocaine enhances HIV-1 replication in CD4+ T cells by down-regulating MiR-125b.

The main objective of this study was to examine effects of cocaine on HIV-1 replication in primary CD4+ T cells. Cocaine a commonly used drug among HIV-1 positive individuals serves as a cofactor for HIV-1 infection and progression to acquired immunodeficiency syndrome (AIDS). Accumulating evidence...

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Bibliographic Details
Main Authors: Chinmay K Mantri, Jui Pandhare Dash, Jyoti Velamarti Mantri, Chandravanu C V Dash
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3520918?pdf=render

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