Oxygen mediated oxidative couplings of flavones in alkaline water
Catalysed oxidative C-C bond formation reactions are important in the synthesis of natural products, but poorly tolerated by polyphenolic flavones. Here the authors report the reactivity of molecular oxygen in alkaline water without added catalyst for the synthesis of a collection of flavone dimers...
| Main Authors: | , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-34123-w |
| _version_ | 1811335110180470784 |
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| author | Xin Yang Sophie Hui Min Lim Jiachen Lin Jie Wu Haidi Tang Fengyue Zhao Fang Liu Chenghua Sun Xiangcheng Shi Yulong Kuang Joanne Yi Hui Toy Ke Du Yuannian Zhang Xiang Wang Mingtai Sun Zhixuan Song Tian Wang Ji’en Wu K. N. Houk Dejian Huang |
| author_facet | Xin Yang Sophie Hui Min Lim Jiachen Lin Jie Wu Haidi Tang Fengyue Zhao Fang Liu Chenghua Sun Xiangcheng Shi Yulong Kuang Joanne Yi Hui Toy Ke Du Yuannian Zhang Xiang Wang Mingtai Sun Zhixuan Song Tian Wang Ji’en Wu K. N. Houk Dejian Huang |
| author_sort | Xin Yang |
| collection | DOAJ |
| description | Catalysed oxidative C-C bond formation reactions are important in the synthesis of natural products, but poorly tolerated by polyphenolic flavones. Here the authors report the reactivity of molecular oxygen in alkaline water without added catalyst for the synthesis of a collection of flavone dimers and trimers. |
| first_indexed | 2024-04-13T17:19:12Z |
| format | Article |
| id | doaj.art-3301a34d2e2d42a28dca474d9561374a |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-13T17:19:12Z |
| publishDate | 2022-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-3301a34d2e2d42a28dca474d9561374a2022-12-22T02:38:02ZengNature PortfolioNature Communications2041-17232022-10-0113111310.1038/s41467-022-34123-wOxygen mediated oxidative couplings of flavones in alkaline waterXin Yang0Sophie Hui Min Lim1Jiachen Lin2Jie Wu3Haidi Tang4Fengyue Zhao5Fang Liu6Chenghua Sun7Xiangcheng Shi8Yulong Kuang9Joanne Yi Hui Toy10Ke Du11Yuannian Zhang12Xiang Wang13Mingtai Sun14Zhixuan Song15Tian Wang16Ji’en Wu17K. N. Houk18Dejian Huang19Department of Food Science and Technology, National University of SingaporeDepartment of Food Science and Technology, National University of SingaporeDepartment of Food Science and Technology, National University of SingaporeDepartment of Chemistry, National University of SingaporeDepartment of Chemistry, National University of SingaporeCollege of Sciences, Nanjing Agricultural UniversityCollege of Sciences, Nanjing Agricultural UniversityDepartment of Chemistry and Biotechnology, FSET, Swinburne University of TechnologyDepartment of Chemistry, National University of SingaporeDepartment of Chemistry, National University of SingaporeDepartment of Food Science and Technology, National University of SingaporeDepartment of Food Science and Technology, National University of SingaporeDepartment of Food Science and Technology, National University of SingaporeDepartment of Food Science and Technology, National University of SingaporeDepartment of Food Science and Technology, National University of SingaporeDepartment of Food Science and Technology, National University of SingaporeDepartment of Chemistry, National University of SingaporeDepartment of Chemistry, National University of SingaporeDepartment of Chemistry and Biochemistry, University of CaliforniaDepartment of Food Science and Technology, National University of SingaporeCatalysed oxidative C-C bond formation reactions are important in the synthesis of natural products, but poorly tolerated by polyphenolic flavones. Here the authors report the reactivity of molecular oxygen in alkaline water without added catalyst for the synthesis of a collection of flavone dimers and trimers.https://doi.org/10.1038/s41467-022-34123-w |
| spellingShingle | Xin Yang Sophie Hui Min Lim Jiachen Lin Jie Wu Haidi Tang Fengyue Zhao Fang Liu Chenghua Sun Xiangcheng Shi Yulong Kuang Joanne Yi Hui Toy Ke Du Yuannian Zhang Xiang Wang Mingtai Sun Zhixuan Song Tian Wang Ji’en Wu K. N. Houk Dejian Huang Oxygen mediated oxidative couplings of flavones in alkaline water Nature Communications |
| title | Oxygen mediated oxidative couplings of flavones in alkaline water |
| title_full | Oxygen mediated oxidative couplings of flavones in alkaline water |
| title_fullStr | Oxygen mediated oxidative couplings of flavones in alkaline water |
| title_full_unstemmed | Oxygen mediated oxidative couplings of flavones in alkaline water |
| title_short | Oxygen mediated oxidative couplings of flavones in alkaline water |
| title_sort | oxygen mediated oxidative couplings of flavones in alkaline water |
| url | https://doi.org/10.1038/s41467-022-34123-w |
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