Biocatalytic production of the antibiotic aurachin D in Escherichia coli

Biocatalytic production of the antibiotic aurachin D in Escherichia coli

Abstract Aurachin D is a potent inhibitor of cytochrome bd oxidases, which are potential targets in the treatment of infectious diseases. In this study, our aim was to improve the biocatalytic production of aurachin D from a quinolone precursor molecule with recombinant Escherichia coli cells expres...

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Bibliographic Details
Main Authors: Sebastian Kruth, Lina Schibajew, Markus Nett
Format: Article
Language:English
Published: SpringerOpen 2022-11-01
Series:AMB Express
Subjects:
Aurachin
Bicistronic design
Escherichia coli
Farnesyltransferase
Heterologous expression
Membrane protein
Online Access:https://doi.org/10.1186/s13568-022-01478-8

Internet

https://doi.org/10.1186/s13568-022-01478-8

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