Perspective: Is Random Monoallelic Expression a Contributor to Phenotypic Variability of Autosomal Dominant Disorders?

Perspective: Is Random Monoallelic Expression a Contributor to Phenotypic Variability of Autosomal Dominant Disorders?

Several factors have been proposed as contributors to interfamilial and intrafamilial phenotypic variability in autosomal dominant disorders, including allelic variation, modifier genes, environmental factors and complex genetic and environmental interactions. However, regardless of the similarity o...

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Bibliografiske detaljer
Main Authors: Baoheng Gui, Jesse Slone, Taosheng Huang
Format: Article
Sprog:English
Udgivet: Frontiers Media S.A. 2017-11-01
Serier:Frontiers in Genetics
Fag:
random monoallelic expression
phenotype
expressivity
autosomal dominant disorders
single cell
Online adgang:http://journal.frontiersin.org/article/10.3389/fgene.2017.00191/full

Internet

http://journal.frontiersin.org/article/10.3389/fgene.2017.00191/full

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