Signatures of positive selection in Toll-like receptor (TLR) genes in mammals

Signatures of positive selection in Toll-like receptor (TLR) genes in mammals

<p>Abstract</p> <p>Background</p> <p>Toll-like receptors (TLRs) are a major class of pattern recognition receptors (PRRs) expressed in the cell surface or membrane compartments of immune and non-immune cells. TLRs are encoded by a multigene family and represent the firs...

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Bibliographic Details
Main Authors: Areal Helena, Abrantes Joana, Esteves Pedro J
Format: Article
Language:English
Published: BMC 2011-12-01
Series:BMC Evolutionary Biology
Subjects:
Toll-like receptors
PAMPs
host-pathogen interaction
adaptive evolution
positive selection
viral TLRs
non-viral TLRs
Online Access:http://www.biomedcentral.com/1471-2148/11/368

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