Low Molecular Weight Chitosan-Coated PLGA Nanoparticles for Pulmonary Delivery of Tobramycin for Cystic Fibrosis

Low Molecular Weight Chitosan-Coated PLGA Nanoparticles for Pulmonary Delivery of Tobramycin for Cystic Fibrosis

(1) Background: Poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) loaded with Tobramycin were prepared using a solvent-evaporation method. (2) Methods: The NPs were coated with low molecular weight chitosan (LMWC) to enhance the mucoadhesiveness of PLGA-NPs. The following w/w ratios of tobram...

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Bibliographic Details
Main Authors: Nusaiba K. Al-Nemrawi, Nid’’A H. Alshraiedeh, Aref L. Zayed, Bashar M. Altaani
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Pharmaceuticals
Subjects:
mucoadhesive nanoparticle
chitosan
PLGA
tobramycin
cystic fibrosis
Online Access:http://www.mdpi.com/1424-8247/11/1/28

Internet

http://www.mdpi.com/1424-8247/11/1/28

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