Molecular Testing and Treatment Strategies in <i>RET</i>-Rearranged NSCLC Patients: Stay on Target to Look Forward

Molecular Testing and Treatment Strategies in <i>RET</i>-Rearranged NSCLC Patients: Stay on Target to Look Forward

<i>RET</i> alterations are recognized as key oncogenic drivers in different cancer types, including non-small cell lung cancer (NSCLC). Multikinase inhibitors (MKIs) with anti-<i>RET</i> activities resulted in variable efficacy with significant toxicities because of low targe...

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Bibliographic Details
Main Authors: Maria Lucia Reale, Valentina Bertaglia, Angela Listì, Silvia Novello, Francesco Passiglia
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Journal of Molecular Pathology
Subjects:
<i>RET</i>
NSCLC
selpercatinib
pralsetinib
next-generation sequencing
acquired resistance
Online Access:https://www.mdpi.com/2673-5261/3/1/3

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