Phase Angle, Inflammation, and Sarcopenia in Late Postoperative Roux-En-Y Gastric Bypass
Sarcopenic obesity is characterized by a disproportion between the amount of muscle to fat. Contrary to most studies evaluating parameters related to sarcopenic obesity in the elderly, this study aims to evaluate the phase angle (PhA) and sarcopenia in young individuals pre- and post-Roux-en-Y gastr...
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| Format: | Article |
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MDPI AG
2023-08-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/15/5124 |
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| author | Gisele Florêncio Aglécio Souza Elinton Chaim Allan Santos Louise Duran Camila Carvalho Sarah Monte Alegre |
| author_facet | Gisele Florêncio Aglécio Souza Elinton Chaim Allan Santos Louise Duran Camila Carvalho Sarah Monte Alegre |
| author_sort | Gisele Florêncio |
| collection | DOAJ |
| description | Sarcopenic obesity is characterized by a disproportion between the amount of muscle to fat. Contrary to most studies evaluating parameters related to sarcopenic obesity in the elderly, this study aims to evaluate the phase angle (PhA) and sarcopenia in young individuals pre- and post-Roux-en-Y gastric bypass. A total of 69 volunteers (46 women and 23 men; 38.5 ± 8.1 years) participated in this study. Body composition and PhA were assessed using BIA. Sarcopenia was assessed using a handgrip strength test (HGS) and gait speed (GS), and appendicular lean mass (ALM) was assessed using Dual Energy X-ray Absorptiometry (DXA). The PhA was significantly lower (<i>p</i> < 0.0007) and the resistance (R) significantly higher (<i>p</i> = 0.0026) in the postoperative group. HGS was negatively correlated with R (r = −0.63669; <i>p</i> < 0.0001), hs-CRP (r = −0.45436; <i>p</i> = 0.0197), and leptin (r = −0.46505; <i>p</i> = 0.0043). GS was negatively correlated with R (r = −0.36220; <i>p</i> = 0.0254), and ALM was negatively correlated with reactance (r = −0.49485; <i>p</i> = 0.0034) and R (r = −0.65797; <i>p</i> ≤ 0.0001). PhA and other components of BIA provide a good correlation with sarcopenia, especially regarding the reduction in muscle function, in an early form, in individuals in the pre- and postoperative period of gastric bypass. |
| first_indexed | 2024-03-11T00:23:13Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T00:23:13Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-331e0c2cf7ee445d8b1a5362e71056712023-11-18T23:09:42ZengMDPI AGJournal of Clinical Medicine2077-03832023-08-011215512410.3390/jcm12155124Phase Angle, Inflammation, and Sarcopenia in Late Postoperative Roux-En-Y Gastric BypassGisele Florêncio0Aglécio Souza1Elinton Chaim2Allan Santos3Louise Duran4Camila Carvalho5Sarah Monte Alegre6Department of Internal Medicine, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas 13083-887, BrazilDepartment of Internal Medicine, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas 13083-887, BrazilDepartment of Surgery, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas 13083-887, BrazilDepartment of Nuclear Medicine, Clinic Hospital, State University of Campinas (UNICAMP), Campinas 13083-887, BrazilDepartment of Internal Medicine, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas 13083-887, BrazilDepartment of Internal Medicine, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas 13083-887, BrazilDepartment of Internal Medicine, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas 13083-887, BrazilSarcopenic obesity is characterized by a disproportion between the amount of muscle to fat. Contrary to most studies evaluating parameters related to sarcopenic obesity in the elderly, this study aims to evaluate the phase angle (PhA) and sarcopenia in young individuals pre- and post-Roux-en-Y gastric bypass. A total of 69 volunteers (46 women and 23 men; 38.5 ± 8.1 years) participated in this study. Body composition and PhA were assessed using BIA. Sarcopenia was assessed using a handgrip strength test (HGS) and gait speed (GS), and appendicular lean mass (ALM) was assessed using Dual Energy X-ray Absorptiometry (DXA). The PhA was significantly lower (<i>p</i> < 0.0007) and the resistance (R) significantly higher (<i>p</i> = 0.0026) in the postoperative group. HGS was negatively correlated with R (r = −0.63669; <i>p</i> < 0.0001), hs-CRP (r = −0.45436; <i>p</i> = 0.0197), and leptin (r = −0.46505; <i>p</i> = 0.0043). GS was negatively correlated with R (r = −0.36220; <i>p</i> = 0.0254), and ALM was negatively correlated with reactance (r = −0.49485; <i>p</i> = 0.0034) and R (r = −0.65797; <i>p</i> ≤ 0.0001). PhA and other components of BIA provide a good correlation with sarcopenia, especially regarding the reduction in muscle function, in an early form, in individuals in the pre- and postoperative period of gastric bypass.https://www.mdpi.com/2077-0383/12/15/5124phase anglesarcopeniasarcopenic obesityobesityRoux-en-Y bypass gastric |
| spellingShingle | Gisele Florêncio Aglécio Souza Elinton Chaim Allan Santos Louise Duran Camila Carvalho Sarah Monte Alegre Phase Angle, Inflammation, and Sarcopenia in Late Postoperative Roux-En-Y Gastric Bypass Journal of Clinical Medicine phase angle sarcopenia sarcopenic obesity obesity Roux-en-Y bypass gastric |
| title | Phase Angle, Inflammation, and Sarcopenia in Late Postoperative Roux-En-Y Gastric Bypass |
| title_full | Phase Angle, Inflammation, and Sarcopenia in Late Postoperative Roux-En-Y Gastric Bypass |
| title_fullStr | Phase Angle, Inflammation, and Sarcopenia in Late Postoperative Roux-En-Y Gastric Bypass |
| title_full_unstemmed | Phase Angle, Inflammation, and Sarcopenia in Late Postoperative Roux-En-Y Gastric Bypass |
| title_short | Phase Angle, Inflammation, and Sarcopenia in Late Postoperative Roux-En-Y Gastric Bypass |
| title_sort | phase angle inflammation and sarcopenia in late postoperative roux en y gastric bypass |
| topic | phase angle sarcopenia sarcopenic obesity obesity Roux-en-Y bypass gastric |
| url | https://www.mdpi.com/2077-0383/12/15/5124 |
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