Global Genome Conformational Programming during Neuronal Development Is Associated with CTCF and Nuclear FGFR1—The Genome Archipelago Model

Global Genome Conformational Programming during Neuronal Development Is Associated with CTCF and Nuclear FGFR1—The Genome Archipelago Model

During the development of mouse embryonic stem cells (ESC) to neuronal committed cells (NCC), coordinated changes in the expression of 2851 genes take place, mediated by the nuclear form of FGFR1. In this paper, widespread differences are demonstrated in the ESC and NCC inter- and intra-chromosomal...

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Bibliographic Details
Main Authors: Brandon Decker, Michal Liput, Hussam Abdellatif, Donald Yergeau, Yongho Bae, Josep M. Jornet, Ewa K. Stachowiak, Michal K. Stachowiak
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
chromatin structure
FGFR1
HoxA
embryonic stem cells
neuronal committed cells
Online Access:https://www.mdpi.com/1422-0067/22/1/347

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