Epidemiological features of traumatic spinal cord injury in China: A systematic review and meta-analysis
BackgroundTraumatic spinal cord injury (TSCI) is a highly fatal and disabling event, and its incidence rate is increasing in China. Therefore, we collated the epidemiological factors of TSCI in different regions of China to update the earlier systematic review published in 2018.MethodWe searched fou...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2023.1131791/full |
| _version_ | 1797866963703169024 |
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| author | Youpeng Hu Lianxin Li Binxue Hong Yizhou Xie Tong Li Chaoqun Feng Fei Yang Yehui Wang Jie Zhang Yang Yu Xiaohong Fan |
| author_facet | Youpeng Hu Lianxin Li Binxue Hong Yizhou Xie Tong Li Chaoqun Feng Fei Yang Yehui Wang Jie Zhang Yang Yu Xiaohong Fan |
| author_sort | Youpeng Hu |
| collection | DOAJ |
| description | BackgroundTraumatic spinal cord injury (TSCI) is a highly fatal and disabling event, and its incidence rate is increasing in China. Therefore, we collated the epidemiological factors of TSCI in different regions of China to update the earlier systematic review published in 2018.MethodWe searched four English and three Chinese electronic databases from 1978 to October 1, 2022. From the included reports, information on sample characteristics, incidence, injury characteristics, prognostic factors, and economic burden was extracted. The selection of data was based on the PRISMA statement. The quality of the included studies was assessed by the Agency for Healthcare Research and Quality (AHRQ) tool. The results of the meta-analysis were presented in the form of pooled frequency and forest plots.ResultsA total of 59 reports (60 studies) from 23 provinces were included, of which 41 were in the Chinese language. The random pooled incidence of TSCI in China was estimated to be 65.15 per million (95% CI: 47.20–83.10 per million), with a range of 6.7 to 569.7 per million. The pooled male-to-female ratio was 1.95:1. The pooled mean age of the cases at the time of injury was 45.4 years. Motor vehicle accidents (MVAs) and high falls were found to be the leading causes of TSCI. Incomplete quadriplegia and AISA/Frankel grade D were the most common types of TSCI. Cervical level injury was the most prevalent. The pooled in-hospital mortality and complication rates for TSCI in China were 3% (95% CI: 2–4%) and 35% (95% CI: 23–47%). Respiratory problems were the most common complication and the leading cause of death.ConclusionCompared with previous studies, the epidemiological data on TSCI in China has changed significantly. A need to update the data over time is essential to implement appropriate preventive measures and formulate interventions according to the characteristics of the Chinese population. |
| first_indexed | 2024-04-09T23:33:48Z |
| format | Article |
| id | doaj.art-33269bc84e7c4b959b108eb7c14085d5 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-09T23:33:48Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Neurology |
| spelling | doaj.art-33269bc84e7c4b959b108eb7c14085d52023-03-20T16:53:09ZengFrontiers Media S.A.Frontiers in Neurology1664-22952023-03-011410.3389/fneur.2023.11317911131791Epidemiological features of traumatic spinal cord injury in China: A systematic review and meta-analysisYoupeng Hu0Lianxin Li1Binxue Hong2Yizhou Xie3Tong Li4Chaoqun Feng5Fei Yang6Yehui Wang7Jie Zhang8Yang Yu9Xiaohong Fan10The Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaThe Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaWest China School of Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, ChinaThe Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaThe Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaThe Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaThe Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaThe Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaThe Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaThe Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaThe Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, ChinaBackgroundTraumatic spinal cord injury (TSCI) is a highly fatal and disabling event, and its incidence rate is increasing in China. Therefore, we collated the epidemiological factors of TSCI in different regions of China to update the earlier systematic review published in 2018.MethodWe searched four English and three Chinese electronic databases from 1978 to October 1, 2022. From the included reports, information on sample characteristics, incidence, injury characteristics, prognostic factors, and economic burden was extracted. The selection of data was based on the PRISMA statement. The quality of the included studies was assessed by the Agency for Healthcare Research and Quality (AHRQ) tool. The results of the meta-analysis were presented in the form of pooled frequency and forest plots.ResultsA total of 59 reports (60 studies) from 23 provinces were included, of which 41 were in the Chinese language. The random pooled incidence of TSCI in China was estimated to be 65.15 per million (95% CI: 47.20–83.10 per million), with a range of 6.7 to 569.7 per million. The pooled male-to-female ratio was 1.95:1. The pooled mean age of the cases at the time of injury was 45.4 years. Motor vehicle accidents (MVAs) and high falls were found to be the leading causes of TSCI. Incomplete quadriplegia and AISA/Frankel grade D were the most common types of TSCI. Cervical level injury was the most prevalent. The pooled in-hospital mortality and complication rates for TSCI in China were 3% (95% CI: 2–4%) and 35% (95% CI: 23–47%). Respiratory problems were the most common complication and the leading cause of death.ConclusionCompared with previous studies, the epidemiological data on TSCI in China has changed significantly. A need to update the data over time is essential to implement appropriate preventive measures and formulate interventions according to the characteristics of the Chinese population.https://www.frontiersin.org/articles/10.3389/fneur.2023.1131791/fulltraumatic spinal cord injuryepidemiological factorsincidenceChinasystematic review and meta-analysis |
| spellingShingle | Youpeng Hu Lianxin Li Binxue Hong Yizhou Xie Tong Li Chaoqun Feng Fei Yang Yehui Wang Jie Zhang Yang Yu Xiaohong Fan Epidemiological features of traumatic spinal cord injury in China: A systematic review and meta-analysis Frontiers in Neurology traumatic spinal cord injury epidemiological factors incidence China systematic review and meta-analysis |
| title | Epidemiological features of traumatic spinal cord injury in China: A systematic review and meta-analysis |
| title_full | Epidemiological features of traumatic spinal cord injury in China: A systematic review and meta-analysis |
| title_fullStr | Epidemiological features of traumatic spinal cord injury in China: A systematic review and meta-analysis |
| title_full_unstemmed | Epidemiological features of traumatic spinal cord injury in China: A systematic review and meta-analysis |
| title_short | Epidemiological features of traumatic spinal cord injury in China: A systematic review and meta-analysis |
| title_sort | epidemiological features of traumatic spinal cord injury in china a systematic review and meta analysis |
| topic | traumatic spinal cord injury epidemiological factors incidence China systematic review and meta-analysis |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2023.1131791/full |
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