Interferon-Tau Exerts Direct Prosurvival and Antiapoptotic Actions in Luteinized Bovine Granulosa Cells

Interferon-Tau Exerts Direct Prosurvival and Antiapoptotic Actions in Luteinized Bovine Granulosa Cells

Abstract Interferon-tau (IFNT), serves as a signal to maintain the corpus luteum (CL) during early pregnancy in domestic ruminants. We investigated here whether IFNT directly affects the function of luteinized bovine granulosa cells (LGCs), a model for large-luteal cells. Recombinant ovine IFNT (roI...

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Bibliographic Details
Main Authors: Raghavendra Basavaraja, Senasige Thilina Madusanka, Jessica N. Drum, Ketan Shrestha, Svetlana Farberov, Milo C. Wiltbank, Roberto Sartori, Rina Meidan
Format: Article
Language:English
Published: Nature Portfolio 2019-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-51152-6

Internet

https://doi.org/10.1038/s41598-019-51152-6

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