Interferon-Tau Exerts Direct Prosurvival and Antiapoptotic Actions in Luteinized Bovine Granulosa Cells
Abstract Interferon-tau (IFNT), serves as a signal to maintain the corpus luteum (CL) during early pregnancy in domestic ruminants. We investigated here whether IFNT directly affects the function of luteinized bovine granulosa cells (LGCs), a model for large-luteal cells. Recombinant ovine IFNT (roI...
Main Authors: | Raghavendra Basavaraja, Senasige Thilina Madusanka, Jessica N. Drum, Ketan Shrestha, Svetlana Farberov, Milo C. Wiltbank, Roberto Sartori, Rina Meidan |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2019-10-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-019-51152-6 |
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