An EGFP Knock-in Zebrafish Experimental Model Used in Evaluation of the Amantadine Drug Safety During Early Cardiogenesis

An EGFP Knock-in Zebrafish Experimental Model Used in Evaluation of the Amantadine Drug Safety During Early Cardiogenesis

BackgroundDrug exposure during gestation or in prematurely born children represents a significant risk to congenital heart disease (CHD). Amantadine is an antiviral agent also effective in the treatment of Parkinson’s disease. However, while its potential side effects associated with tetralogy of fa...

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Bibliographic Details
Main Authors: Shi Ouyang, Wu-Ming Qin, Yu-Juan Niu, Yong-He Ding, Yun Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
zebrafish model
vmhc
amantadine drug
congenital heart disease (CHD)
cardiac development
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.839166/full

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