Identifying a novel role for the master regulator Tal1 in the Endothelial to Hematopoietic Transition

Abstract Progress in the generation of Hematopoietic Stem and Progenitor Cells (HSPCs) in vitro and ex vivo has been built on the knowledge of developmental hematopoiesis, underscoring the importance of understanding this process. HSPCs emerge within the embryonic vasculature through an Endothelial-...

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Bibliographic Details
Main Authors: Yasmin Natalia Serina Secanechia, Isabelle Bergiers, Matt Rogon, Christian Arnold, Nicolas Descostes, Stephanie Le, Natalia López-Anguita, Kerstin Ganter, Chrysi Kapsali, Lea Bouilleau, Aaron Gut, Auguste Uzuotaite, Ayshan Aliyeva, Judith B. Zaugg, Christophe Lancrin
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-20906-0