Elucidating the Metabolic Plasticity of Cancer: Mitochondrial Reprogramming and Hybrid Metabolic States
Aerobic glycolysis, also referred to as the Warburg effect, has been regarded as the dominant metabolic phenotype in cancer cells for a long time. More recently, it has been shown that mitochondria in most tumors are not defective in their ability to carry out oxidative phosphorylation (OXPHOS). Ins...
Main Authors: | Dongya Jia, Jun Hyoung Park, Kwang Hwa Jung, Herbert Levine, Benny Abraham Kaipparettu |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-03-01
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Series: | Cells |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4409/7/3/21 |
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