The Amsterdam Ultra-high field adult lifespan database (AHEAD): A freely available multimodal 7 Tesla submillimeter magnetic resonance imaging database

Normative databases allow testing of novel hypotheses without the costly collection of magnetic resonance imaging (MRI) data. Here we present the Amsterdam Ultra-high field adult lifespan database (AHEAD). The AHEAD consists of 105 7 Tesla (T) whole-brain structural MRI scans tailored specifically t...

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Main Authors: Anneke Alkemade, Martijn J Mulder, Josephine M Groot, Bethany R Isaacs, Nikita van Berendonk, Nicky Lute, Scott JS Isherwood, Pierre-Louis Bazin, Birte U Forstmann
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:NeuroImage
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811920306868
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author Anneke Alkemade
Martijn J Mulder
Josephine M Groot
Bethany R Isaacs
Nikita van Berendonk
Nicky Lute
Scott JS Isherwood
Pierre-Louis Bazin
Birte U Forstmann
author_facet Anneke Alkemade
Martijn J Mulder
Josephine M Groot
Bethany R Isaacs
Nikita van Berendonk
Nicky Lute
Scott JS Isherwood
Pierre-Louis Bazin
Birte U Forstmann
author_sort Anneke Alkemade
collection DOAJ
description Normative databases allow testing of novel hypotheses without the costly collection of magnetic resonance imaging (MRI) data. Here we present the Amsterdam Ultra-high field adult lifespan database (AHEAD). The AHEAD consists of 105 7 Tesla (T) whole-brain structural MRI scans tailored specifically to imaging of the human subcortex, including both male and female participants and covering the entire adult life span (18–80 yrs). We used these data to create probability maps for the subthalamic nucleus, substantia nigra, internal and external segment of the globus pallidus, and the red nucleus. Data was acquired at a submillimeter resolution using a multi-echo (ME) extension of the second gradient-echo image of the MP2RAGE sequence (MP2RAGEME) sequence, resulting in complete anatomical alignment of quantitative, R1-maps, R2*-maps, T1-maps, T1-weighted images, T2*-maps, and quantitative susceptibility mapping (QSM). Quantitative MRI maps, and derived probability maps of basal ganglia structures are freely available for further analyses.
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spelling doaj.art-3338e1fc174b40b0890c70adf7b618ae2022-12-21T23:44:22ZengElsevierNeuroImage1095-95722020-11-01221117200The Amsterdam Ultra-high field adult lifespan database (AHEAD): A freely available multimodal 7 Tesla submillimeter magnetic resonance imaging databaseAnneke Alkemade0Martijn J Mulder1Josephine M Groot2Bethany R Isaacs3Nikita van Berendonk4Nicky Lute5Scott JS Isherwood6Pierre-Louis Bazin7Birte U Forstmann8Integrative Model-based Cognitive Neuroscience Research Unit, University of Amsterdam, , Nieuwe Achtergracht 129B | Room G3.08, Postbus 15926,1001 NK Amsterdam, The Netherlands; Corresponding author.Integrative Model-based Cognitive Neuroscience Research Unit, University of Amsterdam, , Nieuwe Achtergracht 129B | Room G3.08, Postbus 15926,1001 NK Amsterdam, The Netherlands; Psychology and Social Sciences, University of Utrecht, Utrecht, The NetherlandsIntegrative Model-based Cognitive Neuroscience Research Unit, University of Amsterdam, , Nieuwe Achtergracht 129B | Room G3.08, Postbus 15926,1001 NK Amsterdam, The NetherlandsIntegrative Model-based Cognitive Neuroscience Research Unit, University of Amsterdam, , Nieuwe Achtergracht 129B | Room G3.08, Postbus 15926,1001 NK Amsterdam, The Netherlands; Department of Experimental Neurosurgery, Maastricht University Medical Centre, Maastricht, The NetherlandsIntegrative Model-based Cognitive Neuroscience Research Unit, University of Amsterdam, , Nieuwe Achtergracht 129B | Room G3.08, Postbus 15926,1001 NK Amsterdam, The NetherlandsIntegrative Model-based Cognitive Neuroscience Research Unit, University of Amsterdam, , Nieuwe Achtergracht 129B | Room G3.08, Postbus 15926,1001 NK Amsterdam, The Netherlands; Clinical Neuropsychology, Vrije University, Amsterdam, The NetherlandsIntegrative Model-based Cognitive Neuroscience Research Unit, University of Amsterdam, , Nieuwe Achtergracht 129B | Room G3.08, Postbus 15926,1001 NK Amsterdam, The NetherlandsIntegrative Model-based Cognitive Neuroscience Research Unit, University of Amsterdam, , Nieuwe Achtergracht 129B | Room G3.08, Postbus 15926,1001 NK Amsterdam, The Netherlands; Max Planck Institute for Human, Cognitive and Brain Sciences, Leipzig, GermanyIntegrative Model-based Cognitive Neuroscience Research Unit, University of Amsterdam, , Nieuwe Achtergracht 129B | Room G3.08, Postbus 15926,1001 NK Amsterdam, The NetherlandsNormative databases allow testing of novel hypotheses without the costly collection of magnetic resonance imaging (MRI) data. Here we present the Amsterdam Ultra-high field adult lifespan database (AHEAD). The AHEAD consists of 105 7 Tesla (T) whole-brain structural MRI scans tailored specifically to imaging of the human subcortex, including both male and female participants and covering the entire adult life span (18–80 yrs). We used these data to create probability maps for the subthalamic nucleus, substantia nigra, internal and external segment of the globus pallidus, and the red nucleus. Data was acquired at a submillimeter resolution using a multi-echo (ME) extension of the second gradient-echo image of the MP2RAGE sequence (MP2RAGEME) sequence, resulting in complete anatomical alignment of quantitative, R1-maps, R2*-maps, T1-maps, T1-weighted images, T2*-maps, and quantitative susceptibility mapping (QSM). Quantitative MRI maps, and derived probability maps of basal ganglia structures are freely available for further analyses.http://www.sciencedirect.com/science/article/pii/S1053811920306868Ultra-high field 7 Tesla structural MRISubcortexProbabilistic mapsBasal ganglia
spellingShingle Anneke Alkemade
Martijn J Mulder
Josephine M Groot
Bethany R Isaacs
Nikita van Berendonk
Nicky Lute
Scott JS Isherwood
Pierre-Louis Bazin
Birte U Forstmann
The Amsterdam Ultra-high field adult lifespan database (AHEAD): A freely available multimodal 7 Tesla submillimeter magnetic resonance imaging database
NeuroImage
Ultra-high field 7 Tesla structural MRI
Subcortex
Probabilistic maps
Basal ganglia
title The Amsterdam Ultra-high field adult lifespan database (AHEAD): A freely available multimodal 7 Tesla submillimeter magnetic resonance imaging database
title_full The Amsterdam Ultra-high field adult lifespan database (AHEAD): A freely available multimodal 7 Tesla submillimeter magnetic resonance imaging database
title_fullStr The Amsterdam Ultra-high field adult lifespan database (AHEAD): A freely available multimodal 7 Tesla submillimeter magnetic resonance imaging database
title_full_unstemmed The Amsterdam Ultra-high field adult lifespan database (AHEAD): A freely available multimodal 7 Tesla submillimeter magnetic resonance imaging database
title_short The Amsterdam Ultra-high field adult lifespan database (AHEAD): A freely available multimodal 7 Tesla submillimeter magnetic resonance imaging database
title_sort amsterdam ultra high field adult lifespan database ahead a freely available multimodal 7 tesla submillimeter magnetic resonance imaging database
topic Ultra-high field 7 Tesla structural MRI
Subcortex
Probabilistic maps
Basal ganglia
url http://www.sciencedirect.com/science/article/pii/S1053811920306868
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