Early-onset preeclampsia is characterised by an increased vascular tone in internal jugular veins
PurposeThis study aimed to investigate Doppler characteristics of maternal internal jugular veins in uncomplicated pregnancies vs. those affected by hypertensive disorders.Materials and methodsVenous pulse transit time and venous impedance index were measured at three different locations (right prox...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.911059/full |
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| author | Inge Dierickx Inge Dierickx Cécile Kremer Liesbeth Bruckers Wilfried Gyselaers Wilfried Gyselaers |
| author_facet | Inge Dierickx Inge Dierickx Cécile Kremer Liesbeth Bruckers Wilfried Gyselaers Wilfried Gyselaers |
| author_sort | Inge Dierickx |
| collection | DOAJ |
| description | PurposeThis study aimed to investigate Doppler characteristics of maternal internal jugular veins in uncomplicated pregnancies vs. those affected by hypertensive disorders.Materials and methodsVenous pulse transit time and venous impedance index were measured at three different locations (right proximal, right distal, left proximal) of internal jugular veins according to a standardised combined Doppler-Electrocardiogram protocol in five different groups of pregnant women: uncomplicated pregnancy, early-onset preeclampsia, late-onset preeclampsia, gestational hypertension, and normotensive pregnancies with a small for gestational age foetus. Values of both parameters of the latter four groups were plotted against the reference range of uncomplicated pregnancies at corresponding gestation. Linear mixed models with random intercept were used to investigate gestational changes in venous pulse transit time and venous impedance index at the three internal jugular vein locations within and between the different groups.ResultsA total of 127 women were included: 41 had uncomplicated pregnancies, 13 had early-onset preeclampsia, 25 had late-onset preeclampsia, 22 had gestational hypertension, and 26 had normotensive pregnancies with a small for gestational age foetus. Venous pulse transit time values were lower than uncomplicated pregnancy (p ≤ 0.001) at all three locations in the third trimester of early-onset preeclampsia.ConclusionContrary to late-onset preeclampsia and gestational hypertension, early-onset preeclampsia is characterised by a lower venous pulse transit time at internal jugular veins compared to uncomplicated pregnancy, suggesting increased venous vascular tone. |
| first_indexed | 2024-12-10T20:05:57Z |
| format | Article |
| id | doaj.art-333b5f7ed2ac45009ba77de2ee661d75 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-12-10T20:05:57Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-333b5f7ed2ac45009ba77de2ee661d752022-12-22T01:35:24ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2022-08-01910.3389/fcvm.2022.911059911059Early-onset preeclampsia is characterised by an increased vascular tone in internal jugular veinsInge Dierickx0Inge Dierickx1Cécile Kremer2Liesbeth Bruckers3Wilfried Gyselaers4Wilfried Gyselaers5Department of Obstetrics and Gynaecology, Sint Lucas Ziekenhuis, Gent, BelgiumDepartment of Physiology, Hasselt University, Hasselt, BelgiumInteruniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Hasselt, BelgiumInteruniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Hasselt, BelgiumDepartment of Physiology, Hasselt University, Hasselt, BelgiumDepartment of Obstetrics and Gynaecology, East Limburg Hospital, Genk, BelgiumPurposeThis study aimed to investigate Doppler characteristics of maternal internal jugular veins in uncomplicated pregnancies vs. those affected by hypertensive disorders.Materials and methodsVenous pulse transit time and venous impedance index were measured at three different locations (right proximal, right distal, left proximal) of internal jugular veins according to a standardised combined Doppler-Electrocardiogram protocol in five different groups of pregnant women: uncomplicated pregnancy, early-onset preeclampsia, late-onset preeclampsia, gestational hypertension, and normotensive pregnancies with a small for gestational age foetus. Values of both parameters of the latter four groups were plotted against the reference range of uncomplicated pregnancies at corresponding gestation. Linear mixed models with random intercept were used to investigate gestational changes in venous pulse transit time and venous impedance index at the three internal jugular vein locations within and between the different groups.ResultsA total of 127 women were included: 41 had uncomplicated pregnancies, 13 had early-onset preeclampsia, 25 had late-onset preeclampsia, 22 had gestational hypertension, and 26 had normotensive pregnancies with a small for gestational age foetus. Venous pulse transit time values were lower than uncomplicated pregnancy (p ≤ 0.001) at all three locations in the third trimester of early-onset preeclampsia.ConclusionContrary to late-onset preeclampsia and gestational hypertension, early-onset preeclampsia is characterised by a lower venous pulse transit time at internal jugular veins compared to uncomplicated pregnancy, suggesting increased venous vascular tone.https://www.frontiersin.org/articles/10.3389/fcvm.2022.911059/fullcombined Doppler-Electrocardiogramvenous pulse transit timevenous impedance indexpreeclampsiagestational hypertensionvenous maternal haemodynamics |
| spellingShingle | Inge Dierickx Inge Dierickx Cécile Kremer Liesbeth Bruckers Wilfried Gyselaers Wilfried Gyselaers Early-onset preeclampsia is characterised by an increased vascular tone in internal jugular veins Frontiers in Cardiovascular Medicine combined Doppler-Electrocardiogram venous pulse transit time venous impedance index preeclampsia gestational hypertension venous maternal haemodynamics |
| title | Early-onset preeclampsia is characterised by an increased vascular tone in internal jugular veins |
| title_full | Early-onset preeclampsia is characterised by an increased vascular tone in internal jugular veins |
| title_fullStr | Early-onset preeclampsia is characterised by an increased vascular tone in internal jugular veins |
| title_full_unstemmed | Early-onset preeclampsia is characterised by an increased vascular tone in internal jugular veins |
| title_short | Early-onset preeclampsia is characterised by an increased vascular tone in internal jugular veins |
| title_sort | early onset preeclampsia is characterised by an increased vascular tone in internal jugular veins |
| topic | combined Doppler-Electrocardiogram venous pulse transit time venous impedance index preeclampsia gestational hypertension venous maternal haemodynamics |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2022.911059/full |
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