Orofacial clinical manifestations in adult patients with variable common immunodeficiency
Background: Common variable immunodeficiency is the primary immunodeficiency (CVID) frequently found in adults. Its prevalence is estimated from 1:25,000 to 75,000 alive newborns; there are variations by ethnic groups, it is estimated about 50-70% in Caucasian patients. Oral cavity lesions are rarel...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Colegio Mexicano de Inmunología Clínica y Alergia, A.C.
2015-04-01
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| Series: | Revista Alergia México |
| Subjects: | |
| Online Access: | http://revistaalergia.mx/ojs/index.php/ram/article/view/75 |
| _version_ | 1797758216833073152 |
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| author | Aurora Alejandra Chávez-García Miguel Ángel Moreno-Alba Martín Elizalde-Monroy Nora Hilda Segura-Méndez Jovita Romero-Flores Julio César Cambray-Gutiérrez Patricia López-Pérez Leonel Gerardo Del Rivero-Hernández |
| author_facet | Aurora Alejandra Chávez-García Miguel Ángel Moreno-Alba Martín Elizalde-Monroy Nora Hilda Segura-Méndez Jovita Romero-Flores Julio César Cambray-Gutiérrez Patricia López-Pérez Leonel Gerardo Del Rivero-Hernández |
| author_sort | Aurora Alejandra Chávez-García |
| collection | DOAJ |
| description | Background: Common variable immunodeficiency is the primary immunodeficiency (CVID) frequently found in adults. Its prevalence is estimated from 1:25,000 to 75,000 alive newborns; there are variations by ethnic groups, it is estimated about 50-70% in Caucasian patients. Oral cavity lesions are rarely found in adult patients with CVID, there are reports about lesions on pediatric patients mostly caused by infections.
Objective: To describe the orofacial lesions (oral, maxillofacial and neck area) affecting adults with CVID.
Material and method: A transversal, prospective study was done in patients with CVID attended at Specialties Hospital, CMN SXXI, Mexico City. Patients where examined by the oral and maxillofacial surgeon and clinical findings were reported, then the descriptive analysis of the lesions was done.
Results: We evaluated 26 patients, 16 female and 10 males, average age of 38.6 years. In 18/26 patients we found oral lesions on 7 different types. The most frequent was minor salivary glands hiperplasia (19/26), petechiae (12/26) and herpetic ulcers (7/26). In head and neck, we found 4 different lesions, the most common was lymphadenopathy <2cm (4/26).
Conclusions: The immunologic alterations associated to CVID favors the development of lesions mainly of infectious and probably autoinmune origin that affects the oral cavity and head and neck area. |
| first_indexed | 2024-03-12T18:26:51Z |
| format | Article |
| id | doaj.art-333bb00a87454b06b686a187772490fa |
| institution | Directory Open Access Journal |
| issn | 0002-5151 2448-9190 |
| language | English |
| last_indexed | 2024-03-12T18:26:51Z |
| publishDate | 2015-04-01 |
| publisher | Colegio Mexicano de Inmunología Clínica y Alergia, A.C. |
| record_format | Article |
| series | Revista Alergia México |
| spelling | doaj.art-333bb00a87454b06b686a187772490fa2023-08-02T08:31:04ZengColegio Mexicano de Inmunología Clínica y Alergia, A.C.Revista Alergia México0002-51512448-91902015-04-0162210711110.29262/ram.v62i2.7582Orofacial clinical manifestations in adult patients with variable common immunodeficiencyAurora Alejandra Chávez-García0Miguel Ángel Moreno-Alba1Martín Elizalde-Monroy2Nora Hilda Segura-Méndez3Jovita Romero-Flores4Julio César Cambray-Gutiérrez5Patricia López-Pérez6Leonel Gerardo Del Rivero-Hernández7Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades, Servicio de Alergia e Inmunología Clínica, Ciudad de MéxicoInstituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades, Ciudad de MéxicoInstituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades, Ciudad de MéxicoInstituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades, Servicio de Alergia e Inmunología Clínica, Ciudad de MéxicoInstituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades, Ciudad de MéxicoInstituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades, Servicio de Alergia e Inmunología Clínica, Ciudad de MéxicoInstituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades, Servicio de Alergia e Inmunología Clínica, Ciudad de MéxicoInstituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades, Servicio de Alergia e Inmunología Clínica, Ciudad de MéxicoBackground: Common variable immunodeficiency is the primary immunodeficiency (CVID) frequently found in adults. Its prevalence is estimated from 1:25,000 to 75,000 alive newborns; there are variations by ethnic groups, it is estimated about 50-70% in Caucasian patients. Oral cavity lesions are rarely found in adult patients with CVID, there are reports about lesions on pediatric patients mostly caused by infections. Objective: To describe the orofacial lesions (oral, maxillofacial and neck area) affecting adults with CVID. Material and method: A transversal, prospective study was done in patients with CVID attended at Specialties Hospital, CMN SXXI, Mexico City. Patients where examined by the oral and maxillofacial surgeon and clinical findings were reported, then the descriptive analysis of the lesions was done. Results: We evaluated 26 patients, 16 female and 10 males, average age of 38.6 years. In 18/26 patients we found oral lesions on 7 different types. The most frequent was minor salivary glands hiperplasia (19/26), petechiae (12/26) and herpetic ulcers (7/26). In head and neck, we found 4 different lesions, the most common was lymphadenopathy <2cm (4/26). Conclusions: The immunologic alterations associated to CVID favors the development of lesions mainly of infectious and probably autoinmune origin that affects the oral cavity and head and neck area.http://revistaalergia.mx/ojs/index.php/ram/article/view/75inmunodeficiencia común variablelesiones orofacialesalteraciones inmunológicas |
| spellingShingle | Aurora Alejandra Chávez-García Miguel Ángel Moreno-Alba Martín Elizalde-Monroy Nora Hilda Segura-Méndez Jovita Romero-Flores Julio César Cambray-Gutiérrez Patricia López-Pérez Leonel Gerardo Del Rivero-Hernández Orofacial clinical manifestations in adult patients with variable common immunodeficiency Revista Alergia México inmunodeficiencia común variable lesiones orofaciales alteraciones inmunológicas |
| title | Orofacial clinical manifestations in adult patients with variable common immunodeficiency |
| title_full | Orofacial clinical manifestations in adult patients with variable common immunodeficiency |
| title_fullStr | Orofacial clinical manifestations in adult patients with variable common immunodeficiency |
| title_full_unstemmed | Orofacial clinical manifestations in adult patients with variable common immunodeficiency |
| title_short | Orofacial clinical manifestations in adult patients with variable common immunodeficiency |
| title_sort | orofacial clinical manifestations in adult patients with variable common immunodeficiency |
| topic | inmunodeficiencia común variable lesiones orofaciales alteraciones inmunológicas |
| url | http://revistaalergia.mx/ojs/index.php/ram/article/view/75 |
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