Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning Processes
Electrospinning is an inexpensive and powerful method that employs a polymer solution and strong electric field to produce nanofibers. These can be applied in diverse biological and medical applications. Due to their large surface area, controllable surface functionalization and properties, and typi...
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Format: | Article |
Language: | English |
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MDPI AG
2021-07-01
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Series: | Nanomaterials |
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Online Access: | https://www.mdpi.com/2079-4991/11/8/1968 |
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author | Mina Zare Karolina Dziemidowicz Gareth R. Williams Seeram Ramakrishna |
author_facet | Mina Zare Karolina Dziemidowicz Gareth R. Williams Seeram Ramakrishna |
author_sort | Mina Zare |
collection | DOAJ |
description | Electrospinning is an inexpensive and powerful method that employs a polymer solution and strong electric field to produce nanofibers. These can be applied in diverse biological and medical applications. Due to their large surface area, controllable surface functionalization and properties, and typically high biocompatibility electrospun nanofibers are recognized as promising materials for the manufacturing of drug delivery systems. Electrospinning offers the potential to formulate poorly soluble drugs as amorphous solid dispersions to improve solubility, bioavailability and targeting of drug release. It is also a successful strategy for the encapsulation of nutraceuticals. This review aims to briefly discuss the concept of electrospinning and recent progress in manufacturing electrospun drug delivery systems. It will further consider in detail the encapsulation of nutraceuticals, particularly probiotics. |
first_indexed | 2024-03-10T08:31:59Z |
format | Article |
id | doaj.art-333c8b23673d4829b67509f75a7da4b2 |
institution | Directory Open Access Journal |
issn | 2079-4991 |
language | English |
last_indexed | 2024-03-10T08:31:59Z |
publishDate | 2021-07-01 |
publisher | MDPI AG |
record_format | Article |
series | Nanomaterials |
spelling | doaj.art-333c8b23673d4829b67509f75a7da4b22023-11-22T08:58:29ZengMDPI AGNanomaterials2079-49912021-07-01118196810.3390/nano11081968Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning ProcessesMina Zare0Karolina Dziemidowicz1Gareth R. Williams2Seeram Ramakrishna3Center for Nanotechnology and Sustainability, National University of Singapore, Singapore 117581, SingaporeUCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UKUCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UKCenter for Nanotechnology and Sustainability, National University of Singapore, Singapore 117581, SingaporeElectrospinning is an inexpensive and powerful method that employs a polymer solution and strong electric field to produce nanofibers. These can be applied in diverse biological and medical applications. Due to their large surface area, controllable surface functionalization and properties, and typically high biocompatibility electrospun nanofibers are recognized as promising materials for the manufacturing of drug delivery systems. Electrospinning offers the potential to formulate poorly soluble drugs as amorphous solid dispersions to improve solubility, bioavailability and targeting of drug release. It is also a successful strategy for the encapsulation of nutraceuticals. This review aims to briefly discuss the concept of electrospinning and recent progress in manufacturing electrospun drug delivery systems. It will further consider in detail the encapsulation of nutraceuticals, particularly probiotics.https://www.mdpi.com/2079-4991/11/8/1968electrospinningencapsulationnanocarriernanofibernutraceuticalsprobiotics |
spellingShingle | Mina Zare Karolina Dziemidowicz Gareth R. Williams Seeram Ramakrishna Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning Processes Nanomaterials electrospinning encapsulation nanocarrier nanofiber nutraceuticals probiotics |
title | Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning Processes |
title_full | Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning Processes |
title_fullStr | Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning Processes |
title_full_unstemmed | Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning Processes |
title_short | Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning Processes |
title_sort | encapsulation of pharmaceutical and nutraceutical active ingredients using electrospinning processes |
topic | electrospinning encapsulation nanocarrier nanofiber nutraceuticals probiotics |
url | https://www.mdpi.com/2079-4991/11/8/1968 |
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