Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning Processes

Electrospinning is an inexpensive and powerful method that employs a polymer solution and strong electric field to produce nanofibers. These can be applied in diverse biological and medical applications. Due to their large surface area, controllable surface functionalization and properties, and typi...

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Main Authors: Mina Zare, Karolina Dziemidowicz, Gareth R. Williams, Seeram Ramakrishna
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/11/8/1968
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author Mina Zare
Karolina Dziemidowicz
Gareth R. Williams
Seeram Ramakrishna
author_facet Mina Zare
Karolina Dziemidowicz
Gareth R. Williams
Seeram Ramakrishna
author_sort Mina Zare
collection DOAJ
description Electrospinning is an inexpensive and powerful method that employs a polymer solution and strong electric field to produce nanofibers. These can be applied in diverse biological and medical applications. Due to their large surface area, controllable surface functionalization and properties, and typically high biocompatibility electrospun nanofibers are recognized as promising materials for the manufacturing of drug delivery systems. Electrospinning offers the potential to formulate poorly soluble drugs as amorphous solid dispersions to improve solubility, bioavailability and targeting of drug release. It is also a successful strategy for the encapsulation of nutraceuticals. This review aims to briefly discuss the concept of electrospinning and recent progress in manufacturing electrospun drug delivery systems. It will further consider in detail the encapsulation of nutraceuticals, particularly probiotics.
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spelling doaj.art-333c8b23673d4829b67509f75a7da4b22023-11-22T08:58:29ZengMDPI AGNanomaterials2079-49912021-07-01118196810.3390/nano11081968Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning ProcessesMina Zare0Karolina Dziemidowicz1Gareth R. Williams2Seeram Ramakrishna3Center for Nanotechnology and Sustainability, National University of Singapore, Singapore 117581, SingaporeUCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UKUCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UKCenter for Nanotechnology and Sustainability, National University of Singapore, Singapore 117581, SingaporeElectrospinning is an inexpensive and powerful method that employs a polymer solution and strong electric field to produce nanofibers. These can be applied in diverse biological and medical applications. Due to their large surface area, controllable surface functionalization and properties, and typically high biocompatibility electrospun nanofibers are recognized as promising materials for the manufacturing of drug delivery systems. Electrospinning offers the potential to formulate poorly soluble drugs as amorphous solid dispersions to improve solubility, bioavailability and targeting of drug release. It is also a successful strategy for the encapsulation of nutraceuticals. This review aims to briefly discuss the concept of electrospinning and recent progress in manufacturing electrospun drug delivery systems. It will further consider in detail the encapsulation of nutraceuticals, particularly probiotics.https://www.mdpi.com/2079-4991/11/8/1968electrospinningencapsulationnanocarriernanofibernutraceuticalsprobiotics
spellingShingle Mina Zare
Karolina Dziemidowicz
Gareth R. Williams
Seeram Ramakrishna
Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning Processes
Nanomaterials
electrospinning
encapsulation
nanocarrier
nanofiber
nutraceuticals
probiotics
title Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning Processes
title_full Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning Processes
title_fullStr Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning Processes
title_full_unstemmed Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning Processes
title_short Encapsulation of Pharmaceutical and Nutraceutical Active Ingredients Using Electrospinning Processes
title_sort encapsulation of pharmaceutical and nutraceutical active ingredients using electrospinning processes
topic electrospinning
encapsulation
nanocarrier
nanofiber
nutraceuticals
probiotics
url https://www.mdpi.com/2079-4991/11/8/1968
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