Design and Synthesis of Arf1-Targeting γ-Dipeptides as Potential Agents against Head and Neck Squamous Cell Carcinoma

Design and Synthesis of Arf1-Targeting γ-Dipeptides as Potential Agents against Head and Neck Squamous Cell Carcinoma

Background: Head and neck squamous cell carcinoma (HNSCC) is one of the leading causes of cancer-related deaths and calls for new druggable targets. We have previously highlighted the critical role of ADP-ribosylation factor-1 (Arf1) activation in HNSCC. In the present study, we address the question...

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Bibliographic Details
Main Authors: Yen Vo-Hoang, Sergio Paiva, Leilei He, Sébastien Estaran, Yong Teng
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
hnscc
arf1
constrained γ-dipeptides
anticancer
Online Access:https://www.mdpi.com/2073-4409/9/2/286

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