Microgravity crystallization of perdeuterated tryptophan synthase for neutron diffraction

Abstract Biologically active vitamin B6-derivative pyridoxal 5′-phosphate (PLP) is an essential cofactor in amino acid metabolic pathways. PLP-dependent enzymes catalyze a multitude of chemical reactions but, how reaction diversity of PLP-dependent enzymes is achieved is still not well understood. S...

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Bibliographic Details
Main Authors: Victoria N. Drago, Juliette M. Devos, Matthew P. Blakeley, V. Trevor Forsyth, Andrey Y. Kovalevsky, Constance A. Schall, Timothy C. Mueser
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:npj Microgravity
Online Access:https://doi.org/10.1038/s41526-022-00199-3