Silenced LINC01134 Enhances Oxaliplatin Sensitivity by Facilitating Ferroptosis Through GPX4 in Hepatocarcinoma

Silenced LINC01134 Enhances Oxaliplatin Sensitivity by Facilitating Ferroptosis Through GPX4 in Hepatocarcinoma

PurposeRecently, long noncoding RNA LINC01134 has been shown to reduce cell viability and apoptosis via the antioxidant stress pathway, thereby enhancing OXA resistance in hepatocellular carcinoma. However, the association of LINC01134 with ferroptosis and the underlying molecular mechanisms remain...

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Bibliographic Details
Main Authors: Xiaofeng Kang, Yan Huo, Songhao Jia, Fuliang He, Huizi Li, Qing Zhou, Nijia Chang, Donghui Liu, Rongkuan Li, Yi Hu, Ping Zhang, An Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Oncology
Subjects:
linc01134
Nrf2
GPx4
OXA
ferroptosis
HCC cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.939605/full

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