The dual regulation of substance P-mediated inflammation via human synovial mast cells in rheumatoid arthritis

The dual regulation of substance P-mediated inflammation via human synovial mast cells in rheumatoid arthritis

Background: Neural pathways are thought to be directly involved in the pathogenesis of rheumatoid arthritis (RA). Although synovial mast cells (MCs) are activated by substance P (SP), the role of MCs in neural pathways in RA remains unknown. The aims of this study were to investigate 1) whether tach...

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Bibliographic Details
Main Authors: Yuki Okamura, Shintaro Mishima, Jun-ichi Kashiwakura, Tomomi Sasaki-Sakamoto, Shota Toyoshima, Kazumichi Kuroda, Shu Saito, Yasuaki Tokuhashi, Yoshimichi Okayama
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Allergology International
Subjects:
Mast cell
Osteoarthritis
Rheumatoid arthritis
Substance P
Synovium
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893017300229

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