The impact of the genetic background on gene deletion phenotypes in Saccharomyces cerevisiae

The impact of the genetic background on gene deletion phenotypes in Saccharomyces cerevisiae

Abstract Loss‐of‐function (LoF) mutations associated with disease do not manifest equally in different individuals. The impact of the genetic background on the consequences of LoF mutations remains poorly characterized. Here, we systematically assessed the changes in gene deletion phenotypes for 3,7...

Full description

Bibliographic Details
Main Authors: Marco Galardini, Bede P Busby, Cristina Vieitez, Alistair S Dunham, Athanasios Typas, Pedro Beltrao
Format: Article
Language:English
Published: Springer Nature 2019-12-01
Series:Molecular Systems Biology
Subjects:
chemical genomics
genetic background
LoF phenotypes
Saccharomyces cerevisiae
Online Access:https://doi.org/10.15252/msb.20198831

Similar Items

Similar Items