A representative of arylcyanomethylenequinone oximes effectively inhibits growth and formation of hyphae in Candida albicans and influences the activity of protein kinases in vitro

A representative of arylcyanomethylenequinone oximes effectively inhibits growth and formation of hyphae in Candida albicans and influences the activity of protein kinases in vitro

In this study, we applied various assays to reveal new activities of phenylcyanomethylenequinone oxime-4-(hydroxyimino) cyclohexa-2,5-dien-1-ylidene](phenyl)ethanenitrile (4-AN) for potential anti-microbial applications. These assays demonstrated (a) the antimicrobial effect on bacterial and fungal...

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Bibliographic Details
Main Authors: Maciej Masłyk, Monika Janeczko, Oleg M. Demchuk, Anna Boguszewska-Czubara, Hieronim Golczyk, Anna Sierosławska, Anna Rymuszka, Aleksandra Martyna, Konrad Kubiński
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Saudi Pharmaceutical Journal
Subjects:
Arylcyanomethylenequinone oximes
Antifungal agents
Candida albicans
Hyphae
Phosphorylation
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016417302128

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