Associations of Calcium Intake and Calcium from Various Sources with Blood Lipids in a Population of Older Women and Men with High Calcium Intake
Promoting calcium intake is a cornerstone for osteoporosis management. Some individuals limit dairy product consumption, a major calcium source, due to their high content in saturated fats and their perceived negative impact on lipid profiles. This study explored the associations of calcium from var...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/14/6/1314 |
| _version_ | 1797443884711673856 |
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| author | Maria Papageorgiou Fanny Merminod Serge Ferrari René Rizzoli Emmanuel Biver |
| author_facet | Maria Papageorgiou Fanny Merminod Serge Ferrari René Rizzoli Emmanuel Biver |
| author_sort | Maria Papageorgiou |
| collection | DOAJ |
| description | Promoting calcium intake is a cornerstone for osteoporosis management. Some individuals limit dairy product consumption, a major calcium source, due to their high content in saturated fats and their perceived negative impact on lipid profiles. This study explored the associations of calcium from various sources with blood lipids in community-dwelling elderly (<i>n</i> = 717) from the GERICO cohort. Dietary calcium intake was assessed at several timepoints using a validated food frequency questionnaire (FFQ) and calcium supplement use was recorded. Blood lipids were treated as categorical variables to distinguish those with normal and abnormal levels. Increasing total calcium intake was associated with lower risks for high total cholesterol (<i>p</i> = 0.038) and triglycerides (<i>p</i> = 0.007), and low HDL-cholesterol (<i>p</i> = 0.010). Dairy calcium (<i>p</i> = 0.031), especially calcium from milk (<i>p</i> = 0.044) and milk-based desserts (<i>p</i> = 0.039), i.e., low-fat (<i>p</i> = 0.022) and non-fermented (<i>p</i> = 0.005) dairy products, were associated with a lower risk of high total cholesterol. Greater calcium intakes from total dairies (<i>p</i> = 0.020), milk (<i>p</i> = 0.020) and non-fermented dairies (<i>p</i> = 0.027) were associated with a lower risk of hypertriglyceridemia. No association was observed between calcium from non-dairy sources, cheese or high-fat dairies and blood lipids. Increasing calcium through supplements was associated with lower risks for hypertriglyceridemia (<i>p</i> = 0.022) and low HDL-cholesterol (<i>p</i> = 0.001), but not after adjustments. Our results suggest that higher calcium intakes from dietary sources or supplements are not adversely associated with blood lipids in the elderly, whilst total, and particularly low-fat, dairy products are valuable calcium sources potentially related to favorable lipid profiles. |
| first_indexed | 2024-03-09T13:03:34Z |
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| id | doaj.art-334eb8a65a6349f6b0b33b8fb88b292a |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T13:03:34Z |
| publishDate | 2022-03-01 |
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| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-334eb8a65a6349f6b0b33b8fb88b292a2023-11-30T21:51:03ZengMDPI AGNutrients2072-66432022-03-01146131410.3390/nu14061314Associations of Calcium Intake and Calcium from Various Sources with Blood Lipids in a Population of Older Women and Men with High Calcium IntakeMaria Papageorgiou0Fanny Merminod1Serge Ferrari2René Rizzoli3Emmanuel Biver4Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, University of Geneva, 1205 Geneva, SwitzerlandDivision of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, University of Geneva, 1205 Geneva, SwitzerlandDivision of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, University of Geneva, 1205 Geneva, SwitzerlandDivision of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, University of Geneva, 1205 Geneva, SwitzerlandDivision of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, University of Geneva, 1205 Geneva, SwitzerlandPromoting calcium intake is a cornerstone for osteoporosis management. Some individuals limit dairy product consumption, a major calcium source, due to their high content in saturated fats and their perceived negative impact on lipid profiles. This study explored the associations of calcium from various sources with blood lipids in community-dwelling elderly (<i>n</i> = 717) from the GERICO cohort. Dietary calcium intake was assessed at several timepoints using a validated food frequency questionnaire (FFQ) and calcium supplement use was recorded. Blood lipids were treated as categorical variables to distinguish those with normal and abnormal levels. Increasing total calcium intake was associated with lower risks for high total cholesterol (<i>p</i> = 0.038) and triglycerides (<i>p</i> = 0.007), and low HDL-cholesterol (<i>p</i> = 0.010). Dairy calcium (<i>p</i> = 0.031), especially calcium from milk (<i>p</i> = 0.044) and milk-based desserts (<i>p</i> = 0.039), i.e., low-fat (<i>p</i> = 0.022) and non-fermented (<i>p</i> = 0.005) dairy products, were associated with a lower risk of high total cholesterol. Greater calcium intakes from total dairies (<i>p</i> = 0.020), milk (<i>p</i> = 0.020) and non-fermented dairies (<i>p</i> = 0.027) were associated with a lower risk of hypertriglyceridemia. No association was observed between calcium from non-dairy sources, cheese or high-fat dairies and blood lipids. Increasing calcium through supplements was associated with lower risks for hypertriglyceridemia (<i>p</i> = 0.022) and low HDL-cholesterol (<i>p</i> = 0.001), but not after adjustments. Our results suggest that higher calcium intakes from dietary sources or supplements are not adversely associated with blood lipids in the elderly, whilst total, and particularly low-fat, dairy products are valuable calcium sources potentially related to favorable lipid profiles.https://www.mdpi.com/2072-6643/14/6/1314calcium intakecalcium supplementsdairy consumptionfermented dairy productslow-fat dairy productsdyslipidemia |
| spellingShingle | Maria Papageorgiou Fanny Merminod Serge Ferrari René Rizzoli Emmanuel Biver Associations of Calcium Intake and Calcium from Various Sources with Blood Lipids in a Population of Older Women and Men with High Calcium Intake Nutrients calcium intake calcium supplements dairy consumption fermented dairy products low-fat dairy products dyslipidemia |
| title | Associations of Calcium Intake and Calcium from Various Sources with Blood Lipids in a Population of Older Women and Men with High Calcium Intake |
| title_full | Associations of Calcium Intake and Calcium from Various Sources with Blood Lipids in a Population of Older Women and Men with High Calcium Intake |
| title_fullStr | Associations of Calcium Intake and Calcium from Various Sources with Blood Lipids in a Population of Older Women and Men with High Calcium Intake |
| title_full_unstemmed | Associations of Calcium Intake and Calcium from Various Sources with Blood Lipids in a Population of Older Women and Men with High Calcium Intake |
| title_short | Associations of Calcium Intake and Calcium from Various Sources with Blood Lipids in a Population of Older Women and Men with High Calcium Intake |
| title_sort | associations of calcium intake and calcium from various sources with blood lipids in a population of older women and men with high calcium intake |
| topic | calcium intake calcium supplements dairy consumption fermented dairy products low-fat dairy products dyslipidemia |
| url | https://www.mdpi.com/2072-6643/14/6/1314 |
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