Identification of New L-Fucosyl and L-Galactosyl Amides as Glycomimetic Ligands of TNF Lectin Domain of BC2L-C from <i>Burkholderia cenocepacia</i>

Identification of New L-Fucosyl and L-Galactosyl Amides as Glycomimetic Ligands of TNF Lectin Domain of BC2L-C from <i>Burkholderia cenocepacia</i>

The inhibition of carbohydrate-lectin interactions is being explored as an efficient approach to anti adhesion therapy and biofilm destabilization, two alternative antimicrobial strategies that are being explored against resistant pathogens. BC2L-C is a new type of lectin from <i>Burkholderia ...

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Bibliographic Details
Main Authors: Sarah Mazzotta, Giulia Antonini, Francesca Vasile, Emilie Gillon, Jon Lundstrøm, Annabelle Varrot, Laura Belvisi, Anna Bernardi
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Molecules
Subjects:
lectins
fucosides
<i>N</i>-glycosides
crystallography
glycomimetics
antiadhesive therapy
Online Access:https://www.mdpi.com/1420-3049/28/3/1494

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