Cotinine Plus Krill Oil Decreased Depressive Behavior, and Increased Astrocytes Survival in the Hippocampus of Mice Subjected to Restraint Stress

Cotinine Plus Krill Oil Decreased Depressive Behavior, and Increased Astrocytes Survival in the Hippocampus of Mice Subjected to Restraint Stress

Restraint stress (RS) is a condition affecting millions of people worldwide. The investigation of new therapies to alleviate the consequences of prolonged RS is much needed. Cotinine, a nicotine-derivative, has shown to prevent the decrease in cerebral synaptic density, working memory deficits, anxi...

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Bibliographic Details
Main Authors: Cristhian Mendoza, Nelson Perez-Urrutia, Nathalie Alvarez-Ricartes, George E. Barreto, Raquel Pérez-Ordás, Alex Iarkov, Valentina Echeverria
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Neuroscience
Subjects:
depression
cotinine
anxiety
restraint stress
krill oil
astrocytes
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00952/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2018.00952/full

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