The impact of specific balneotherapy on the endocrine physio-pathological mechanism in obesity
Obesity is a complex, multifactorial metabolic pathology, within the path of modification of the endocrine system plays a significant role. Changes in growth hormone (GH) and in-sulin growth factor (IGF) have been associated with obesity in various ways, mainly through changes in GH-binding proteins...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Romanian Association of Balneology, Editura Balneara
2023-03-01
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| Series: | Balneo and PRM Research Journal |
| Subjects: | |
| Online Access: | http://bioclima.ro/Balneo542.pdf |
| _version_ | 1827973392401170432 |
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| author | Liliana-Elena Stanciu Andreea- Bianca Uzun Mădălina-Gabriela Iliescu Carmen Oprea Doinița Oprea Elena-Valentina Ionescu Claudia Ileana Mihailov |
| author_facet | Liliana-Elena Stanciu Andreea- Bianca Uzun Mădălina-Gabriela Iliescu Carmen Oprea Doinița Oprea Elena-Valentina Ionescu Claudia Ileana Mihailov |
| author_sort | Liliana-Elena Stanciu |
| collection | DOAJ |
| description | Obesity is a complex, multifactorial metabolic pathology, within the path of modification of the endocrine system plays a significant role. Changes in growth hormone (GH) and in-sulin growth factor (IGF) have been associated with obesity in various ways, mainly through changes in GH-binding proteins, insulin and ghrelin levels. The balneal treat-ment with Techirghiol Romanian sapropelic mud has an important impact on the endo-crine system, primarily through the action on the hypothalamic-pituitary-adrenal axis. We investigated the secretory changes of the IGF-1 hormone that appeared after the balne-al treatment. It was a total number of 52 patients, divided into two groups: 1 group who performed the treatment with Techirghiol sapropelic mud at thermoneutrality tempera-tures - warm mud baths, and the second group who followed treatment with the balneal therapeutic factor in a thermal contrast regime - cold mud baths. We studied whether there are correlations between the body mass index (BMI) and the secretion of this hor-mone. We also determined the serum levels of blood glucose at admission and discharge. In the cold mud baths- thermal contrast therapy, can be observed a statistically significant increase in IGF-1 values during the balneal treatment (p = 0.044 < α = 0.05). Comparative-ly, in the warm mud baths, the increase in serum IGF-1 reached values close to statistical significance at the end of the treatment (p = 0.067 > α = 0.05). There were no statistically significant correlations between BMI and IGF-1 hormone secretion at admission and at discharge. The results showed a statistically significant decrease in blood glucose values determined at admission and discharge in the group that performed warm mud baths. The balneal treatment with sapropelic mud of Techirghiol lake, from Romania, through the impact on the endocrine system, on the hypothalamic-pituitary-adrenal axis, can be registered as a treatment with a natural therapeutic factor with an impact on obesity, ther-apy carried out within the parameters of metabolic safety, and the conduct of future re-search in this direction it will help develop new concepts and approaches to obesity. |
| first_indexed | 2024-04-09T19:35:20Z |
| format | Article |
| id | doaj.art-33525e2f7a4e4fc894c70d9cac750588 |
| institution | Directory Open Access Journal |
| issn | 2734-8458 |
| language | English |
| last_indexed | 2024-04-09T19:35:20Z |
| publishDate | 2023-03-01 |
| publisher | Romanian Association of Balneology, Editura Balneara |
| record_format | Article |
| series | Balneo and PRM Research Journal |
| spelling | doaj.art-33525e2f7a4e4fc894c70d9cac7505882023-04-04T11:47:28ZengRomanian Association of Balneology, Editura BalnearaBalneo and PRM Research Journal2734-84582023-03-0114154210.12680/balneo.2023.542The impact of specific balneotherapy on the endocrine physio-pathological mechanism in obesityLiliana-Elena Stanciu0Andreea- Bianca Uzun1Mădălina-Gabriela Iliescu2Carmen Oprea3Doinița Oprea4Elena-Valentina Ionescu5Claudia Ileana Mihailov6„Ovidius” University of Constanta, Faculty of Medicine, 1 University Alley, Campus – Corp B, 900470, Constanta, Romania„Ovidius” University of Constanta, Faculty of Medicine, 1 University Alley, Campus – Corp B, 900470, Constanta, Romania„Ovidius” University of Constanta, Faculty of Medicine, 1 University Alley, Campus – Corp B, 900470, Constanta, Romania„Ovidius” University of Constanta, Faculty of Medicine, 1 University Alley, Campus – Corp B, 900470, Constanta, Romania„Ovidius” University of Constanta, Faculty of Medicine, 1 University Alley, Campus – Corp B, 900470, Constanta, Romania„Ovidius” University of Constanta, Faculty of Medicine, 1 University Alley, Campus – Corp B, 900470, Constanta, Romania„Ovidius” University of Constanta, Faculty of Medicine, 1 University Alley, Campus – Corp B, 900470, Constanta, RomaniaObesity is a complex, multifactorial metabolic pathology, within the path of modification of the endocrine system plays a significant role. Changes in growth hormone (GH) and in-sulin growth factor (IGF) have been associated with obesity in various ways, mainly through changes in GH-binding proteins, insulin and ghrelin levels. The balneal treat-ment with Techirghiol Romanian sapropelic mud has an important impact on the endo-crine system, primarily through the action on the hypothalamic-pituitary-adrenal axis. We investigated the secretory changes of the IGF-1 hormone that appeared after the balne-al treatment. It was a total number of 52 patients, divided into two groups: 1 group who performed the treatment with Techirghiol sapropelic mud at thermoneutrality tempera-tures - warm mud baths, and the second group who followed treatment with the balneal therapeutic factor in a thermal contrast regime - cold mud baths. We studied whether there are correlations between the body mass index (BMI) and the secretion of this hor-mone. We also determined the serum levels of blood glucose at admission and discharge. In the cold mud baths- thermal contrast therapy, can be observed a statistically significant increase in IGF-1 values during the balneal treatment (p = 0.044 < α = 0.05). Comparative-ly, in the warm mud baths, the increase in serum IGF-1 reached values close to statistical significance at the end of the treatment (p = 0.067 > α = 0.05). There were no statistically significant correlations between BMI and IGF-1 hormone secretion at admission and at discharge. The results showed a statistically significant decrease in blood glucose values determined at admission and discharge in the group that performed warm mud baths. The balneal treatment with sapropelic mud of Techirghiol lake, from Romania, through the impact on the endocrine system, on the hypothalamic-pituitary-adrenal axis, can be registered as a treatment with a natural therapeutic factor with an impact on obesity, ther-apy carried out within the parameters of metabolic safety, and the conduct of future re-search in this direction it will help develop new concepts and approaches to obesity.http://bioclima.ro/Balneo542.pdfobesityendocrine systemigf-1mud therapybalneotherapy |
| spellingShingle | Liliana-Elena Stanciu Andreea- Bianca Uzun Mădălina-Gabriela Iliescu Carmen Oprea Doinița Oprea Elena-Valentina Ionescu Claudia Ileana Mihailov The impact of specific balneotherapy on the endocrine physio-pathological mechanism in obesity Balneo and PRM Research Journal obesity endocrine system igf-1 mud therapy balneotherapy |
| title | The impact of specific balneotherapy on the endocrine physio-pathological mechanism in obesity |
| title_full | The impact of specific balneotherapy on the endocrine physio-pathological mechanism in obesity |
| title_fullStr | The impact of specific balneotherapy on the endocrine physio-pathological mechanism in obesity |
| title_full_unstemmed | The impact of specific balneotherapy on the endocrine physio-pathological mechanism in obesity |
| title_short | The impact of specific balneotherapy on the endocrine physio-pathological mechanism in obesity |
| title_sort | impact of specific balneotherapy on the endocrine physio pathological mechanism in obesity |
| topic | obesity endocrine system igf-1 mud therapy balneotherapy |
| url | http://bioclima.ro/Balneo542.pdf |
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