Interrogating breast cancer heterogeneity using single and pooled circulating tumor cell analysis

Abstract Single cell technologies allow the interrogation of tumor heterogeneity, providing insights into tumor evolution and treatment resistance. To better understand whether circulating tumor cells (CTCs) could complement metastatic biopsies for tumor genomic profiling, we characterized 11 single...

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Bibliographic Details
Main Authors: Françoise Rothé, David Venet, Dieter Peeters, Ghizlane Rouas, Mattia Rediti, Dominiek Smeets, Floriane Dupont, Peter Campbell, Diether Lambrechts, Luc Dirix, Christos Sotiriou, Michail Ignatiadis
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-022-00445-7