ROS-Drp1-mediated mitochondria fission contributes to hippocampal HT22 cell apoptosis induced by silver nanoparticles

ROS-Drp1-mediated mitochondria fission contributes to hippocampal HT22 cell apoptosis induced by silver nanoparticles

Silver nanoparticles (AgNPs) have widely used in industrial and medical applications for their excellent antibacterial activities. AgNPs can penetrate into the brain and cause neuronal death, but limited evidence focused on toxic effects and mechanic study in hippocampal neuron. This study aimed to...

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Bibliographic Details
Main Authors: Xiaoru Chang, Shuyan Niu, Mengting Shang, Jiangyan Li, Menghao Guo, Wenli Zhang, Zuoyi Sun, Yunjing Li, Rui Zhang, Xin Shen, Meng Tang, Yuying Xue
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Redox Biology
Subjects:
Silver nanoparticles
Neurotoxicity
Mitochondrial fission
Drp1
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723001404

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