Cryospray ablation (CSA) in the palliative treatment of squamous cell carcinoma of the esophagus

<p>Abstract</p> <p>Background</p> <p>Esophageal carcinoma is the ninth most prevalent cancer worldwide with squamous cell carcinoma (SCCA) and adenocarcinoma accounting for the vast majority of new cases (13,900 in 2003). Cure rates in the U.S. are less than 10%, simila...

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Main Authors: Johnston Mark H, Johnston Lavonne R, Cash Brooks D
Format: Article
Language:English
Published: BMC 2007-03-01
Series:World Journal of Surgical Oncology
Online Access:http://www.wjso.com/content/5/1/34
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author Johnston Mark H
Johnston Lavonne R
Cash Brooks D
author_facet Johnston Mark H
Johnston Lavonne R
Cash Brooks D
author_sort Johnston Mark H
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Esophageal carcinoma is the ninth most prevalent cancer worldwide with squamous cell carcinoma (SCCA) and adenocarcinoma accounting for the vast majority of new cases (13,900 in 2003). Cure rates in the U.S. are less than 10%, similar to lung cancer. More than 50% of patients with esophageal carcinoma present with unresectable or metastatic disease, are not surgical candidates, or display disease progression despite the addition of neoadjuvant chemoradiotherapy to surgery. Need for improved palliation exits.</p> <p>Case presentation</p> <p>This case describes a 73-year-old African American male who presented with recurrent squamous cell carcinoma (SCCA) of the esophagus who has a achieved complete remission for 24 months via endoscopic cryospray ablation.</p> <p>Conclusion</p> <p>Endoscopic cryo spray ablation warrants further investigation as a palliative treatment modality for esophageal cancer. This is the first reported case in the medical literature.</p>
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spelling doaj.art-335ec022454d45c9992ae8c9b69bc4b82022-12-22T03:29:42ZengBMCWorld Journal of Surgical Oncology1477-78192007-03-01513410.1186/1477-7819-5-34Cryospray ablation (CSA) in the palliative treatment of squamous cell carcinoma of the esophagusJohnston Mark HJohnston Lavonne RCash Brooks D<p>Abstract</p> <p>Background</p> <p>Esophageal carcinoma is the ninth most prevalent cancer worldwide with squamous cell carcinoma (SCCA) and adenocarcinoma accounting for the vast majority of new cases (13,900 in 2003). Cure rates in the U.S. are less than 10%, similar to lung cancer. More than 50% of patients with esophageal carcinoma present with unresectable or metastatic disease, are not surgical candidates, or display disease progression despite the addition of neoadjuvant chemoradiotherapy to surgery. Need for improved palliation exits.</p> <p>Case presentation</p> <p>This case describes a 73-year-old African American male who presented with recurrent squamous cell carcinoma (SCCA) of the esophagus who has a achieved complete remission for 24 months via endoscopic cryospray ablation.</p> <p>Conclusion</p> <p>Endoscopic cryo spray ablation warrants further investigation as a palliative treatment modality for esophageal cancer. This is the first reported case in the medical literature.</p>http://www.wjso.com/content/5/1/34
spellingShingle Johnston Mark H
Johnston Lavonne R
Cash Brooks D
Cryospray ablation (CSA) in the palliative treatment of squamous cell carcinoma of the esophagus
World Journal of Surgical Oncology
title Cryospray ablation (CSA) in the palliative treatment of squamous cell carcinoma of the esophagus
title_full Cryospray ablation (CSA) in the palliative treatment of squamous cell carcinoma of the esophagus
title_fullStr Cryospray ablation (CSA) in the palliative treatment of squamous cell carcinoma of the esophagus
title_full_unstemmed Cryospray ablation (CSA) in the palliative treatment of squamous cell carcinoma of the esophagus
title_short Cryospray ablation (CSA) in the palliative treatment of squamous cell carcinoma of the esophagus
title_sort cryospray ablation csa in the palliative treatment of squamous cell carcinoma of the esophagus
url http://www.wjso.com/content/5/1/34
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AT johnstonlavonner cryosprayablationcsainthepalliativetreatmentofsquamouscellcarcinomaoftheesophagus
AT cashbrooksd cryosprayablationcsainthepalliativetreatmentofsquamouscellcarcinomaoftheesophagus